MedKoo Cat#: 572111 | Name: t-Boc-N-amido-PEG1-NHS ester
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

t-Boc-N-amido-PEG1-NHS ester is a Boc-protected PEG linker. The Boc group can be deprotected under acidic conditions to generate a free amine group. PEG Linkers may be useful in the development of antibody drug conjugates (ADCs).

Chemical Structure

t-Boc-N-amido-PEG1-NHS ester
t-Boc-N-amido-PEG1-NHS ester
CAS#1260092-55-4

Theoretical Analysis

MedKoo Cat#: 572111

Name: t-Boc-N-amido-PEG1-NHS ester

CAS#: 1260092-55-4

Chemical Formula: C14H22N2O7

Exact Mass: 330.1427

Molecular Weight: 330.34

Elemental Analysis: C, 50.90; H, 6.71; N, 8.48; O, 33.90

Price and Availability

Size Price Availability Quantity
250mg USD 560.00
500mg USD 870.00
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
t-Boc-N-amido-PEG1-NHS ester
IUPAC/Chemical Name
2,5-dioxopyrrolidin-1-yl 3-(2-((tert-butoxycarbonyl)amino)ethoxy)propanoate
InChi Key
KTMOAQDFUHQKJY-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H22N2O7/c1-14(2,3)22-13(20)15-7-9-21-8-6-12(19)23-16-10(17)4-5-11(16)18/h4-9H2,1-3H3,(H,15,20)
SMILES Code
CC(C)(C)OC(NCCOCCC(ON1C(CCC1=O)=O)=O)=O
Appearance
Solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 330.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zhang P, Huang Y, Liu H, Marquez RT, Lu J, Zhao W, Zhang X, Gao X, Li J, Venkataramanan R, Xu L, Li S. A PEG-Fmoc conjugate as a nanocarrier for paclitaxel. Biomaterials. 2014 Aug;35(25):7146-56. doi: 10.1016/j.biomaterials.2014.04.108. Epub 2014 May 22. PubMed PMID: 24856103; PubMed Central PMCID: PMC4102141. 2: Salmaso S, Bersani S, Scomparin A, Mastrotto F, Scherpfer R, Tonon G, Caliceti P. Tailored PEG for rh-G-CSF analogue site-specific conjugation. Bioconjug Chem. 2009 Jun;20(6):1179-85. doi: 10.1021/bc9000432. PubMed PMID: 19469471.