MedKoo Cat#: 558443 | Name: HUHS2002

Description:

WARNING: This product is for research use only, not for human or veterinary use.

HUHS2002 is a free fatty acid derivative that acts as a potentiator of GluA1 AMPA receptor responses and α7 ACh receptor responses.

Chemical Structure

HUHS2002
HUHS2002
CAS#1393102-59-4

Theoretical Analysis

MedKoo Cat#: 558443

Name: HUHS2002

CAS#: 1393102-59-4

Chemical Formula: C17H24O3

Exact Mass: 276.1700

Molecular Weight: 276.38

Elemental Analysis: C, 73.88; H, 8.75; O, 17.37

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
HUHS2002; HUHS-2002; HUHS 2002;
IUPAC/Chemical Name
4-[4-(Z)-Hept-1-enyl-phenoxy] butyric acid
InChi Key
UISWKZAGZZSFDP-SOFGYWHQSA-N
InChi Code
InChI=1S/C17H24O3/c1-2-3-4-5-6-8-15-10-12-16(13-11-15)20-14-7-9-17(18)19/h6,8,10-13H,2-5,7,9,14H2,1H3,(H,18,19)/b8-6+
SMILES Code
O=C(O)CCCOC1=CC=C(/C=C/CCCCC)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 276.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kanno T, Shimizu T, Tanaka A, Nishimoto T, Nishizaki T. Free fatty acid derivative HUHS2002 potentiates α7 ACh receptor responses through indirect activation of CaMKII. Lipids. 2012 Sep;47(9):865-71. doi: 10.1007/s11745-012-3701-2. Epub 2012 Jul 21. PubMed PMID: 22820984. 2: Nishimoto T, Kanno T, Shimizu T, Tanaka A, Nishizaki T. Regulation of GluA1 AMPA receptor through PKC phosphorylation induced by free fatty acid derivative HUHS2002. Lipids. 2013 Jan;48(1):23-8. doi: 10.1007/s11745-012-3736-4. Epub 2012 Nov 2. PubMed PMID: 23117296; PubMed Central PMCID: PMC3535402.