Synonym
l-trans-Phenothrin;
IUPAC/Chemical Name
3-phenoxybenzyl (1S,3S)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylate
InChi Key
SBNFWQZLDJGRLK-LEWJYISDSA-N
InChi Code
InChI=1S/C23H26O3/c1-16(2)13-20-21(23(20,3)4)22(24)25-15-17-9-8-12-19(14-17)26-18-10-6-5-7-11-18/h5-14,20-21H,15H2,1-4H3/t20-,21+/m0/s1
SMILES Code
O=C([C@@H]1C(C)(C)[C@H]1/C=C(C)\C)OCC2=CC=CC(OC3=CC=CC=C3)=C2
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
350.45
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Xu S, Li H, Wang X, Chen C, Cao M, Cao X. Asymmetric syntheses and bio-evaluation of novel chiral esters derived from substituted tetrafluorobenzyl alcohol. Bioorg Med Chem Lett. 2014 Jun 15;24(12):2734-6. doi: 10.1016/j.bmcl.2014.04.055. Epub 2014 Apr 21. PubMed PMID: 24794106.
2: Kasat K, Go V, Pogo BG. Effects of pyrethroid insecticides and estrogen on WNT10B proto-oncogene expression. Environ Int. 2002 Nov;28(5):429-32. PubMed PMID: 12437293.
3: Berger-Preiss E, Koch W, Gerling S, Kock H, Appel KE. Use of biocidal products (insect sprays and electro-vaporizer) in indoor areas--exposure scenarios and exposure modeling. Int J Hyg Environ Health. 2009 Sep;212(5):505-18. doi: 10.1016/j.ijheh.2009.02.001. Epub 2009 Mar 31. PubMed PMID: 19345645.
4: Saito K, Tomigahara Y, Ohe N, Isobe N, Nakatsuka I, Kaneko H. Lack of significant estrogenic or antiestrogenic activity of pyrethroid insecticides in three in vitro assays based on classic estrogen receptor alpha-mediated mechanisms. Toxicol Sci. 2000 Sep;57(1):54-60. PubMed PMID: 10966511.
5: Feng D, Ke C, Li S, Lu C, Guo F. Pyrethroids as promising marine antifoulants: laboratory and field studies. Mar Biotechnol (NY). 2009 Mar-Apr;11(2):153-60. doi: 10.1007/s10126-008-9130-9. Epub 2008 Jul 25. PubMed PMID: 18654821.
6: Leng G, Gries W. Simultaneous determination of pyrethroid and pyrethrin metabolites in human urine by gas chromatography-high resolution mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Jan 25;814(2):285-94. PubMed PMID: 15639450.
7: Leng G, Gries W, Selim S. Biomarker of pyrethrum exposure. Toxicol Lett. 2006 Apr 10;162(2-3):195-201. Epub 2005 Oct 27. PubMed PMID: 16257148.
8: Lopez-Monroy B, Gutierrez-Rodriguez SM, Villanueva-Segura OK, Ponce-Garcia G, Morales-Forcada F, Alvarez LC, Flores AE. Frequency and intensity of pyrethroid resistance through the CDC bottle bioassay and their association with the frequency of kdr mutations in Aedes aegypti (Diptera: Culicidae) from Mexico. Pest Manag Sci. 2018 Mar 25. doi: 10.1002/ps.4916. [Epub ahead of print] PubMed PMID: 29575404.
-5547.jpg "Voriconazole, (R,R)-")