Haloperidide | CAS#2924-46-1 | antiemetic

MedKoo Cat#: 461037 | Name: Haloperidide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Haloperidide is an antiemetic agent.

Chemical Structure

Haloperidide

CAS#2924-46-1

Theoretical Analysis

MedKoo Cat#: 461037

Name: Haloperidide

CAS#: 2924-46-1

Chemical Formula: C26H30ClFN2O2

Exact Mass: 456.1980

Molecular Weight: 456.98

Elemental Analysis: C, 68.34; H, 6.62; Cl, 7.76; F, 4.16; N, 6.13; O, 7.00

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Haloperidide; R 3201; R-3201; R3201;

IUPAC/Chemical Name

4-(4-(3-chlorophenyl)-4-(pyrrolidine-1-carbonyl)piperidin-1-yl)-1-(4-fluorophenyl)butan-1-one

InChi Key

KCDNYRPDKSGQCM-UHFFFAOYSA-N

InChi Code

InChI=1S/C26H30ClFN2O2/c27-22-6-3-5-21(19-22)26(25(32)30-15-1-2-16-30)12-17-29(18-13-26)14-4-7-24(31)20-8-10-23(28)11-9-20/h3,5-6,8-11,19H,1-2,4,7,12-18H2

SMILES Code

O=C(N1CCCC1)C2(C3=CC=CC(Cl)=C3)CCN(CCCC(C4=CC=C(F)C=C4)=O)CC2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 456.98 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: JANSSEN PA. [Comparative pharmacological data on 6 new basic 4'-fluorobutyrophenone derivatives:haloperidol, haloanisone, triperidol, methylperidide, haloperidide and dipiperone. 2]. Arzneimittelforschung. 1961 Oct;11:932-8. German. PubMed PMID: 14451237. 2: JANSSEN PA, NIEMEGEERS C. Haloperidide (R 3201), a highly potent and selective anti-emetic agent in dogs. Nature. 1961 Jun 3;190:911-2. PubMed PMID: 13789499. 3: NIEMEGEERS CJ, JANSSEN PA. Influence of haloperidol (R 1625) and of haloperidide (R 3201) on avoidance and escape behavior of trained dogs in a "jumping box". J Pharm Pharmacol. 1960 Dec;12:744-53. PubMed PMID: 13728969. 4: JANSSEN PA. [Comparative pharmacological data on 6 new basic 4'-fluorobutyrophenone derivatives:haloperidol, haloanisone, triperidol, methylperidide, haloperidide and dipiperone. 1]. Arzneimittelforschung. 1961 Sep;11:819-24. German. PubMed PMID: 14451236. 5: SCHAPER WK, JAGENEAU AH, HUYGENS J, JANSSEN PA. [The influence of haloperidol (R 1625) and haloperidide (R 3201) on the general behavior of the South American death's head monkey (saimiri)]. Med Exp Int J Exp Med. 1960;3:169-76. German. PubMed PMID: 13747259.