NSC-84096 | CAS#908813-78-5 | rBoNT/A-LC inhibitor

MedKoo Cat#: 558419 | Name: NSC-84096

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NSC-84096 is an inhibitor of endopeptidase activity of botulinum neurotoxin type A light chain (rBoNT/A-LC).

Chemical Structure

NSC-84096

CAS#908813-78-5

Theoretical Analysis

MedKoo Cat#: 558419

Name: NSC-84096

CAS#: 908813-78-5

Chemical Formula: C25H19N3O

Exact Mass: 377.1500

Molecular Weight: 377.45

Elemental Analysis: C, 79.55; H, 5.07; N, 11.13; O, 4.24

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

NSC-84096; NSC 84096; NSC84096; CID-256758; CID 256758; CID256758;

IUPAC/Chemical Name

7-[phenyl-(quinolin-8-ylamino)methyl]quinolin-8-ol

InChi Key

RBSPENDGIMQZGB-UHFFFAOYSA-N

InChi Code

InChI=1S/C25H19N3O/c29-25-20(14-13-19-11-6-16-27-24(19)25)22(17-7-2-1-3-8-17)28-21-12-4-9-18-10-5-15-26-23(18)21/h1-16,22,28-29H

SMILES Code

OC1=C2N=CC=CC2=CC=C1C(C3=CC=CC=C3)NC4=C5N=CC=CC5=CC=C4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 377.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Singh P, Singh MK, Chaudhary D, Chauhan V, Bharadwaj P, Pandey A, Upadhyay N, Dhaked RK. Small-molecule quinolinol inhibitor identified provides protection against BoNT/A in mice. PLoS One. 2012;7(10):e47110. doi: 10.1371/journal.pone.0047110. Epub 2012 Oct 11. Retraction in: PLoS One. 2013;8(9). doi: 10.1371/annotation/049f74d0-919f-483c-a488-4740ec0a5f4d. PubMed PMID: 23071727; PubMed Central PMCID: PMC3469547.