MedKoo Cat#: 592196 | Name: 6-Thioguanosine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

6-Thioguanosine is an Antineoplastic agent.

Chemical Structure

 6-Thioguanosine
6-Thioguanosine
CAS#85-31-4 (free base)

Theoretical Analysis

MedKoo Cat#: 592196

Name: 6-Thioguanosine

CAS#: 85-31-4 (free base)

Chemical Formula: C10H13N5O5S

Exact Mass: 315.0637

Molecular Weight: 315.30

Elemental Analysis: C, 38.09; H, 4.16; N, 22.21; O, 25.37; S, 10.17

Price and Availability

Size Price Availability Quantity
50mg USD 250.00 2 Weeks
100mg USD 450.00 2 Weeks
200mg USD 750.00 2 Weeks
500mg USD 1,650.00 2 Weeks
1g USD 2,950.00 2 Weeks
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Synonym
6-Thioguanosine; NSC-29422; NSC 29422; NSC29422
IUPAC/Chemical Name
2-Amino-6-mercaptopurin-9-ylriboside
InChi Key
NGNLNJVCNSFIAI-LZGMGDPASA-N
InChi Code
InChI=1S/C10H13N5O5S/c11-10-13-7-4(8(21)14-10)12-2-15(7)20-9-6(18)5(17)3(1-16)19-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,21)/t3-,5-,6-,9?/m1/s1
SMILES Code
O[C@H]([C@@H]([C@@H](CO)O1)O)C1ON2C=NC3=C(S)N=C(N)N=C23
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 315.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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PLoS One. 2015 May 11;10(5):e0126256. doi: 10.1371/journal.pone.0126256. eCollection 2015. PubMed PMID: 25961288; PubMed Central PMCID: PMC4427445. 12: Oshiro I, Jitsuzaki D, Onizuka K, Nishimoto A, Taniguchi Y, Sasaki S. Site-specific modification of the 6-amino group of adenosine in RNA by an interstrand functionality-transfer reaction with an s-functionalized 4-thiothymidine. Chembiochem. 2015 May 26;16(8):1199-204. doi: 10.1002/cbic.201500084. Epub 2015 May 4. PubMed PMID: 25940822. 13: De Nicolò A, Agnesod D, Simiele M, Riganò D, Adriani A, Canaparo R, Astegiano M, Rizzetto M, Di Perri G, D'Avolio A. UPLC-MS/MS method for quantification of the azathioprine metabolites 6-mercaptoguanosine and 6-methylmercaptopurine riboside in peripheral blood mononuclear cells. J Pharm Biomed Anal. 2014 Sep;98:271-8. doi: 10.1016/j.jpba.2014.05.040. Epub 2014 Jun 7. PubMed PMID: 24960235. 14: Jitsuzaki D, Onizuka K, Nishimoto A, Oshiro I, Taniguchi Y, Sasaki S. 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