Ophiocarpine | CAS#478-13-7 | protoberberine alkaloid

MedKoo Cat#: 597682 | Name: Ophiocarpine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ophiocarpine is a protoberberine alkaloid.

Chemical Structure

Ophiocarpine

CAS#478-13-7

Theoretical Analysis

MedKoo Cat#: 597682

Name: Ophiocarpine

CAS#: 478-13-7

Chemical Formula: C20H21NO5

Exact Mass: 355.1420

Molecular Weight: 355.39

Elemental Analysis: C, 67.59; H, 5.96; N, 3.94; O, 22.51

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Ophiocarpine; l-Ophiocarpine;

IUPAC/Chemical Name

9,10-dimethoxy-5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-13-ol

InChi Key

FLSSXYPKPLFNLK-UHFFFAOYSA-N

InChi Code

InChI=1S/C20H21NO5/c1-23-15-4-3-12-14(20(15)24-2)9-21-6-5-11-7-16-17(26-10-25-16)8-13(11)18(21)19(12)22/h3-4,7-8,18-19,22H,5-6,9-10H2,1-2H3

SMILES Code

OC1C2=CC=C(OC)C(OC)=C2CN3CCC4=C(C=C5OCOC5=C4)C13

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 355.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: OHTA M, TANI H, MOROZUMI S, KODAIRA S. THE STEREOCHEMISTRY OF HYDRASTINE, NARCOTINE, OPHIOCARPINE, AND THEIR DERIVATIVES. II. ABSOLUTE CONFIGURATION OF NARCOTINE AND THEIR DERIVATIVES. Chem Pharm Bull (Tokyo). 1964 Sep;12:1080-9. PubMed PMID: 14245270. 2: OHTA M, TANI H, MOROZUMI S. THE STEREOCHEMISTRY OF HYDRASTINE, NARCOTINE, OPHIOCARPINE, AND THEIR DERIVATIVES. I. ABSOLUTE CONFIGURATION OF HYDRASTINE AND OPHIOCARPINE. Chem Pharm Bull (Tokyo). 1964 Sep;12:1072-80. PubMed PMID: 14245904. 3: Jeffs PW, Scharver JD. Biosynthesis of ophiocarpine. Introduction of a stereospecific label through transannular cyclization. J Am Chem Soc. 1976 Jul 7;98(14):4301-10. PubMed PMID: 932362. 4: Kametani T, Matsumoto H, Satoh Y, Nemoto H, Fukumoto K. Studies on the syntheses of heterocyclic compounds. Part 679. A stereoselective total synthesis of (+/-)-ophiocarpine; a simple route to 13-hydroxyberbines. J Chem Soc Perkin 1. 1977;4:376-82. PubMed PMID: 557491.