NCT-14b is a selective HDAC6 inhibitor. It inhibits cell growth of α-positive MCF-7 breast cancer cells treated with estrogen but not untreated cells.
MedKoo Cat#: 558385
Name: NCT-14b
CAS#: 956154-63-5
Chemical Formula: C26H44N2O4S
Exact Mass: 480.3022
Molecular Weight: 480.71
Elemental Analysis: C, 64.96; H, 9.23; N, 5.83; O, 13.31; S, 6.67
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 20.0 | 41.61 | |
| Ethanol | 20.0 | 41.61 |
The following data is based on the product molecular weight 480.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
