Synonym
ML356; ML-356; ML 356;
IUPAC/Chemical Name
2-Ethyl-N-[4-(4-morpholin-4-ylsulfonylphenyl)-1,3-thiazol-2-yl]butanamide
InChi Key
YKNITTNJEATJKT-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H25N3O4S2/c1-3-14(4-2)18(23)21-19-20-17(13-27-19)15-5-7-16(8-6-15)28(24,25)22-9-11-26-12-10-22/h5-8,13-14H,3-4,9-12H2,1-2H3,(H,20,21,23)
SMILES Code
CCC(CC)C(NC1=NC(C2=CC=C(S(=O)(N3CCOCC3)=O)C=C2)=CS1)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
Preparing Stock Solutions
The following data is based on the
product
molecular weight
423.54
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Ardecky R, Hedrick MP, Gosalia P, Yamamoto F, Milewski M, Barron N, Sun Q, Zhou J, Ganji S, Mehta A, Sugarman E, Nguyen K, Vasile S, Suyama E, Teriete P, Sheffler D, Lee PS, Mattmann M, De Ingeniis J, Stonich D, Mangravita-Novo A, Salaniwal S, Kung P, Diwan J, Smith LH, Sergienko E, Chung TDY, Pinkerton AB, Cosford NDP, Smith JW. Selective inhibitors of FAS-TE. 2013 Apr 12 [updated 2014 Jan 13]. Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-. Available from http://www.ncbi.nlm.nih.gov/books/NBK189923/ PubMed PMID: 24624464.
