MedKoo Cat#: 526346 | Name: BMS-770767

Description:

WARNING: This product is for research use only, not for human or veterinary use.

BMS-770767 is a novel inhibitor of 11-betahydroxysteroid dehydrogenase type I (11ß-HSD1).

Chemical Structure

BMS-770767
BMS-770767
CAS#1875067-34-7

Theoretical Analysis

MedKoo Cat#: 526346

Name: BMS-770767

CAS#: 1875067-34-7

Chemical Formula: C19H18ClN3O2

Exact Mass: 355.1088

Molecular Weight: 355.82

Elemental Analysis: C, 64.14; H, 5.10; Cl, 9.96; N, 11.81; O, 8.99

Price and Availability

Related CAS #
No Data
Synonym
BMS-770767; BMS 770767; BMS770767;
IUPAC/Chemical Name
4-[8-(2-Chlorophenoxy)-1,2,4-triazolo[4,3-a]pyridin-3-yl]-bicyclo[2.2.1]heptan-1-ol
InChi Key
HNXGIFYHJKEXNA-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H18ClN3O2/c20-13-4-1-2-5-14(13)25-15-6-3-11-23-16(15)21-22-17(23)18-7-9-19(24,12-18)10-8-18/h1-6,11,24H,7-10,12H2
SMILES Code
OC1(C2)CCC2(C3=NN=C4C(OC5=CC=CC=C5Cl)=CC=CN43)CC1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Certificate of Analysis
Safety Data Sheet (SDS)

Preparing Stock Solutions

The following data is based on the product molecular weight 355.82 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Maxwell BD, Bonacorsi SJ Jr. The synthesis and analysis of [phenyl-(14) C(U)]BMS-770767 and [(13) C(6) ]BMS-770767 for use in discovery biotransformation, human ADME and bioanalytical studies. J Labelled Comp Radiopharm. 2016 Dec;59(14):657-664. doi: 10.1002/jlcr.3428. Epub 2016 Jul 27. PubMed PMID: 27460954.