Glycyllysine | CAS#997-62-6 | dipeptide

MedKoo Cat#: 597539 | Name: Glycyllysine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Glycyllysine is a dipeptide. It can be used to study the interactions of lysine side chain with copper in Glycyl-L-lysine-copper(II) complex.

Chemical Structure

Glycyllysine

CAS#997-62-6

Theoretical Analysis

MedKoo Cat#: 597539

Name: Glycyllysine

CAS#: 997-62-6

Chemical Formula: C8H17N3O3

Exact Mass: 203.1270

Molecular Weight: 203.24

Elemental Analysis: C, 47.28; H, 8.43; N, 20.68; O, 23.62

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Glycyllysine; Gly-lys; Glycyl-L-lysine;

IUPAC/Chemical Name

glycyl-L-lysine

InChi Key

IKAIKUBBJHFNBZ-LURJTMIESA-N

InChi Code

InChI=1S/C8H17N3O3/c9-4-2-1-3-6(8(13)14)11-7(12)5-10/h6H,1-5,9-10H2,(H,11,12)(H,13,14)/t6-/m0/s1

SMILES Code

NCCCC[C@@H](C(O)=O)NC(CN)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 203.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Al-Dulaymi MA, Chitanda JM, Mohammed-Saeid W, Araghi HY, Verrall RE, Grochulski P, Badea I. Di-Peptide-Modified Gemini Surfactants as Gene Delivery Vectors: Exploring the Role of the Alkyl Tail in Their Physicochemical Behavior and Biological Activity. AAPS J. 2016 Sep;18(5):1168-81. doi: 10.1208/s12248-016-9906-1. Epub 2016 May 16. PubMed PMID: 27184577. 2: Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. doi: 10.1074/mcp.M112.017905. Epub 2012 Jul 11. PubMed PMID: 22790023; PubMed Central PMCID: PMC3518112. 3: Aquilina JA, Carver JA, Truscott RJ. Elucidation of a novel polypeptide cross-link involving 3-hydroxykynurenine. Biochemistry. 1999 Aug 31;38(35):11455-64. PubMed PMID: 10471297. 4: Aquilina JA, Carver JA, Truscott RJ. Polypeptide modification and cross-linking by oxidized 3-hydroxykynurenine. Biochemistry. 2000 Dec 26;39(51):16176-84. PubMed PMID: 11123946. 5: Xi M, Hai C, Tang H, Wen A, Chen H, Liu R, Liang X, Chen M. Antioxidant and antiglycation properties of triterpenoid saponins from Aralia taibaiensis traditionally used for treating diabetes mellitus. Redox Rep. 2010;15(1):20-8. doi: 10.1179/174329210X12650506623041. PubMed PMID: 20196925. 6: Karidi K, Ypsilantis K, Papakyriakou A, Garoufis A. Synthesis and characterization of ruthenium(II)-oligopyridine-peptide conjugates. Interactions of the diasteromeres Δ- and Λ-[Ru(bpy)2(4-COY-4'-Mebpy)]Cl2 (Y=Gly-Lys(1)-Lys(2)CONH2, Lys(1)-Gly-Lys(2)CONH2, Lys(1)-Lys(2)-GlyCONH2) with the oligonucleotide d(5'-CGCGAATTCGCG-3')2. J Inorg Biochem. 2013 Oct;127:13-23. doi: 10.1016/j.jinorgbio.2013.06.010. Epub 2013 Jun 24. PubMed PMID: 23838117. 7: Endo T, Miyagi M, Ujiie A. Simultaneous determination of glycyl-L-histidyl-L-lysine and its metabolite, L-histidyl-L-lysine, in rat plasma by high-performance liquid chromatography with post-column derivatization. J Chromatogr B Biomed Sci Appl. 1997 Apr 25;692(1):37-42. PubMed PMID: 9187381. 8: Sterner G, Lindberg T, Denneberg T. In vivo and vitro absorption of amino acids and dipeptides in the small intestine of uremic rats. Nephron. 1982;31(3):273-6. PubMed PMID: 6811961. 9: Adesokan AA, Gerber RB. Anharmonic vibrational spectroscopy calculations for proton-bound amino acid dimers. J Phys Chem A. 2009 Mar 12;113(10):1905-12. doi: 10.1021/jp807106h. PubMed PMID: 19061325. 10: Jun YJ, Min JH, Ji da E, Yoo JH, Kim JH, Lee HJ, Jeong B, Sohn YS. A micellar prodrug of paclitaxel conjugated to cyclotriphosphazene. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6410-3. doi: 10.1016/j.bmcl.2008.10.077. Epub 2008 Oct 22. PubMed PMID: 18990574. 11: Cao F, Gamble AB, Onagi H, Howes J, Hennessy JE, Gu C, Morgan JAM, Easton CJ. Detection of Biosynthetic Precursors, Discovery of Glycosylated Forms, and Homeostasis of Calcitonin in Human Cancer Cells. Anal Chem. 2017 Jul 5;89(13):6992-6999. doi: 10.1021/acs.analchem.7b00457. Epub 2017 Jun 14. PubMed PMID: 28590120. 12: Singh J, Michel D, Chitanda JM, Verrall RE, Badea I. Evaluation of cellular uptake and intracellular trafficking as determining factors of gene expression for amino acid-substituted gemini surfactant-based DNA nanoparticles. J Nanobiotechnology. 2012 Feb 1;10:7. doi: 10.1186/1477-3155-10-7. PubMed PMID: 22296763; PubMed Central PMCID: PMC3298462. 13: Singh J, Yang P, Michel D, Verrall RE, Foldvari M, Badea I. Amino acid-substituted gemini surfactant-based nanoparticles as safe and versatile gene delivery agents. Curr Drug Deliv. 2011 May;8(3):299-306. PubMed PMID: 21291379. 14: Oh HB, Lin C, Hwang HY, Zhai H, Breuker K, Zabrouskov V, Carpenter BK, McLafferty FW. Infrared photodissociation spectroscopy of electrosprayed ions in a Fourier transform mass spectrometer. J Am Chem Soc. 2005 Mar 23;127(11):4076-83. PubMed PMID: 15771545. 15: Uehara T, Koike M, Nakata H, Hanaoka H, Iida Y, Hashimoto K, Akizawa H, Endo K, Arano Y. Design, synthesis, and evaluation of [188Re]organorhenium-labeled antibody fragments with renal enzyme-cleavable linkage for low renal radioactivity levels. Bioconjug Chem. 2007 Jan-Feb;18(1):190-8. PubMed PMID: 17226973. 16: Fujioka Y, Satake S, Uehara T, Mukai T, Akizawa H, Ogawa K, Saji H, Endo K, Arano Y. In vitro system to estimate renal brush border enzyme-mediated cleavage of Peptide linkages for designing radiolabeled antibody fragments of low renal radioactivity levels. Bioconjug Chem. 2005 Nov-Dec;16(6):1610-6. PubMed PMID: 16287261. 17: Arano Y, Fujioka Y, Akizawa H, Ono M, Uehara T, Wakisaka K, Nakayama M, Sakahara H, Konishi J, Saji H. Chemical design of radiolabeled antibody fragments for low renal radioactivity levels. Cancer Res. 1999 Jan 1;59(1):128-34. PubMed PMID: 9892197. 18: Mukai T, Fujioka Y, Arano Y, Saji H. [Design of radiolabeled antibody fragments for tumor-selective radioactivity localization--brush border enzyme-sensitive bond to decrease renal accumulation of radioactivity]. Yakugaku Zasshi. 2003 Aug;123(8):647-52. Review. Japanese. PubMed PMID: 12931660. 19: Yang P, Singh J, Wettig S, Foldvari M, Verrall RE, Badea I. Enhanced gene expression in epithelial cells transfected with amino acid-substituted gemini nanoparticles. Eur J Pharm Biopharm. 2010 Aug;75(3):311-20. doi: 10.1016/j.ejpb.2010.04.007. Epub 2010 Apr 22. PubMed PMID: 20417276.