Scaritoxin | CAS#66231-73-0 | toxin

MedKoo Cat#: 461904 | Name: Scaritoxin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Scaritoxin is a potent toxic substance isolated from poisonous fish.

Chemical Structure

Scaritoxin

CAS#66231-73-0

Theoretical Analysis

MedKoo Cat#: 461904

Name: Scaritoxin

CAS#: 66231-73-0

Chemical Formula: C60H84O16

Exact Mass: 1060.5759

Molecular Weight: 1061.31

Elemental Analysis: C, 67.90; H, 7.98; O, 24.12

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Scaritoxin;

IUPAC/Chemical Name

(1'S,2S,2'S,2a'R,5'S,6'S,6a'R,7a'S,8a'R,9a'S,10a'S,11a'S,15a'R,16a'S,18a'R,19a'S,20'R,20a'R,22'S,25a'S,26a'S,27a'S,28a'R,30a'R,31a'R,33'R,33a'R,34a'R,36'R,37a'S,38a'R,E)-22'-((E)-buta-1,3-dien-1-yl)-1',5',6',33a',36'-pentamethyl-1',2a',4,5,5',6',6a',7a',8',8a',9a',10',10a',11a',12',15',15a',16a',18a',19a',20',20a',22',25',25a',26a',27',27a',28a',30a',31a',32',33',33a',34a',35',36',37',37a',38a'-tetracontahydro-2'H,3H-spiro[furan-2,4'-oxepino[2'''',3'''':5''',6''']pyrano[2''',3''':5'',6'']pyrano[2'',3'':6',7']oxepino[2',3':6,7]oxepino[3,2-b]pyrano[2''''',3''''':6'''',7'''']oxepino[2'''',3'''':5''',6''']pyrano[2''',3''':7'',8'']oxocino[2'',3'':5',6']pyrano[2',3':6,7]oxepino[2,3-h]oxonine]-2',20',33'-triol

InChi Key

QFYRPKKCVYDHFZ-QDNORUMCSA-N

InChi Code

InChI=1S/C60H84O16/c1-7-8-13-34-14-11-17-41-56(65-34)53(63)57-49(69-41)26-43-40(72-57)21-20-38-39(67-43)19-18-37-35(66-38)15-9-10-16-36-45(68-37)28-50(61)59(6)51(71-36)29-46-47(75-59)25-30(2)24-42-44(70-46)27-48-54(73-42)32(4)52(62)58-55(74-48)31(3)33(5)60(76-58)22-12-23-64-60/h7-11,13-14,18-21,30-58,61-63H,1,12,15-17,22-29H2,2-6H3/b10-9+,13-8+/t30-,31+,32+,33+,34-,35-,36+,37-,38+,39-,40-,41+,42+,43+,44-,45-,46+,47-,48+,49+,50-,51+,52+,53-,54-,55-,56+,57-,58-,59-,60+/m1/s1

SMILES Code

C=C/C=C/[C@@H](O1)C=CC[C@H](O[C@H]2C3)[C@H]1[C@@H](O)[C@@H]2O[C@H](C=C4)[C@H]3O[C@H](C=C[C@H]5O6)[C@H]4O[C@@H]5C/C=C/C[C@H](O[C@H]7C8)[C@H]6C[C@@H](O)[C@@]7(C)O[C@H](C[C@H](C)C[C@@H]9O[C@@H]%10[C@@H](C)[C@H](O)[C@H]%11O%12)[C@H]8O[C@@H]9C[C@@H]%10O[C@@H]%11[C@@H](C)[C@H](C)[C@]%13%12OCCC%13

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.03.00

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,061.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Boivin R, Bost J, Rentler JF. [Autonomic effects of scaritoxin in the cat and guinea pig. Cardiac protection by an anti-arrhythmia agent]. C R Seances Soc Biol Fil. 1983;177(2):203-10. French. PubMed PMID: 6224540. 2: Tatsumi M, Kajiwara A, Yasumoto T, Ohizumi Y. Potent excitatory effect of scaritoxin on the guinea-pig vas deferens, taenia caeci and ileum. J Pharmacol Exp Ther. 1985 Dec;235(3):783-7. PubMed PMID: 4078732. 3: Endean R, Griffith JK, Robins JJ, Monks SA. Multiple toxins in a specimen of the narrow-barred Spanish mackerel, Scomberomorus commersoni. Toxicon. 1993 Feb;31(2):195-204. PubMed PMID: 8456447. 4: Chungue E, Bagnis R, Fusetani N, Yasumoto T. [Toxic complex from parrotfish]. Biochimie. 1977;59(8-9):739-41. French. PubMed PMID: 597503. 5: Endean R, Monks SA, Griffith JK, Llewellyn LE. Apparent relationships between toxins elaborated by the cyanobacterium Trichodesmium erythraeum and those present in the flesh of the narrow-barred Spanish mackerel Scomberomorus commersoni. Toxicon. 1993 Sep;31(9):1155-65. PubMed PMID: 8266348. 6: Legrand AM, Galonnier M, Bagnis R. Studies on the mode of action of ciguateric toxins. Toxicon. 1982;20(1):311-5. PubMed PMID: 7080044. 7: Satake M, Ishibashi Y, Legrand AM, Yasumoto T. Isolation and structure of ciguatoxin-4A, a new ciguatoxin precursor, from cultures of dinoflagellate Gambierdiscus toxicus and parrotfish Scarus gibbus. Biosci Biotechnol Biochem. 1996 Dec;60(12):2103-5. PubMed PMID: 9026141. 8: Endean R, Griffith JK, Robins JJ, Llewellyn LE, Monks SA. Variation in the toxins present in ciguateric narrow-barred Spanish mackerel, Scomberomorus commersoni. Toxicon. 1993 Jun;31(6):723-32. PubMed PMID: 8342170.