Congo red | CAS#573-58-0 | acid dye

MedKoo Cat#: 558162 | Name: Congo red

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Congo red is an acid dye used in testing for hydrochloric acid in gastric contents. It is also used histologically to test for AMYLOIDOSIS.

Chemical Structure

Congo red

CAS#573-58-0

Theoretical Analysis

MedKoo Cat#: 558162

Name: Congo red

CAS#: 573-58-0

Chemical Formula: C32H22N6Na2O6S2

Exact Mass: 0.0000

Molecular Weight: 696.66

Elemental Analysis: C, 55.17; H, 3.18; N, 12.06; Na, 6.60; O, 13.78; S, 9.20

Price and Availability

Size	Price	Availability	Quantity
5g	USD 250.00	2 Weeks
25g	USD 450.00	2 Weeks

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Related CAS #

No Data

Synonym

DIRECT RED 28; C.I. Direct Red 28; Congo Red 4B; C.I. 22120; NSC-7232; NSC7232; NSC 7232; NSC-56651; NSC56651; NSC 56651

IUPAC/Chemical Name

1-Naphthalenesulfonic acid, 3,3'-((1,1'-biphenyl)-4,4'-diylbis(azo))bis(4-amino-, disodium salt

InChi Key

IQFVPQOLBLOTPF-HKXUKFGYSA-L

InChi Code

InChI=1S/C32H24N6O6S2.2Na/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34;;/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44);;/q;2*+1/p-2/b37-35+,38-36+;;

SMILES Code

O=S(C1=C2C=CC=CC2=C(N)C(/N=N/C3=CC=C(C4=CC=C(/N=N/C5=CC(S(=O)([O-])=O)=C6C=CC=CC6=C5N)C=C4)C=C3)=C1)([O-])=O.[Na+].[Na+]

Appearance

Solid powder

Purity

>95% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 696.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Clement CG, Truong LD. An evaluation of Congo red fluorescence for the diagnosis of amyloidosis. Hum Pathol. 2014 Aug;45(8):1766-72. doi: 10.1016/j.humpath.2014.04.016. Epub 2014 May 8. PubMed PMID: 24935061. 2: Reichhardt C, Jacobson AN, Maher MC, Uang J, McCrate OA, Eckart M, Cegelski L. Congo Red Interactions with Curli-Producing E. coli and Native Curli Amyloid Fibers. PLoS One. 2015 Oct 20;10(10):e0140388. doi: 10.1371/journal.pone.0140388. eCollection 2015. PubMed PMID: 26485271; PubMed Central PMCID: PMC4618944. 3: Mnif I, Fendri R, Ghribi D. Biosorption of Congo Red from aqueous solution by Bacillus weihenstephanensis RI12; effect of SPB1 biosurfactant addition on biodecolorization potency. Water Sci Technol. 2015;72(6):865-74. doi: 10.2166/wst.2015.288. PubMed PMID: 26360745. 4: Jagusiak A, Konieczny L, Krol M, Marszalek P, Piekarska B, Piwowar P, Roterman I, Rybarska J, Stopa B, Zemanek G. Intramolecular immunological signal hypothesis revived--structural background of signalling revealed by using Congo Red as a specific tool. Mini Rev Med Chem. 2015;14(13):1104-13. Review. PubMed PMID: 25429660; PubMed Central PMCID: PMC4440395. 5: Hernández-Zamora M, Perales-Vela HV, Flores-Ortíz CM, Cañizares-Villanueva RO. Physiological and biochemical responses of Chlorella vulgaris to Congo red. Ecotoxicol Environ Saf. 2014 Oct;108:72-7. doi: 10.1016/j.ecoenv.2014.05.030. Epub 2014 Jul 18. PubMed PMID: 25042247. 6: de Vasconcelos DN, Ximenes VF. Albumin-induced circular dichroism in Congo red: Applications for studies of amyloid-like fibril aggregates and binding sites. Spectrochim Acta A Mol Biomol Spectrosc. 2015;150:321-30. doi: 10.1016/j.saa.2015.05.089. Epub 2015 May 30. PubMed PMID: 26056983. 7: Jadhav AH, Zhang H, Agyemang FO, Hiremath V, Lee K, Chandradass J, Seo JG, Kim H. Preparation and Characterization of Electro-Spun Fabricated Ag-TiO2 Composite Nanofibers and Its Enhanced Photo-Catalytic Activity for the Degradation of Congo Red. J Nanosci Nanotechnol. 2015 Oct;15(10):7988-96. PubMed PMID: 26726452. 8: Cooksey CJ. Quirks of dye nomenclature. 2. Congo red. Biotech Histochem. 2014 Jul;89(5):384-7. doi: 10.3109/10520295.2014.880513. Epub 2014 Feb 13. PubMed PMID: 24520883. 9: Cheng Z, Zhang L, Guo X, Jiang X, Li T. Adsorption behavior of direct red 80 and congo red onto activated carbon/surfactant: process optimization, kinetics and equilibrium. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Feb 25;137:1126-43. doi: 10.1016/j.saa.2014.08.138. Epub 2014 Sep 23. PubMed PMID: 25305604. 10: Habibi MH, Rahmati MH. The effect of operational parameters on the photocatalytic degradation of Congo red organic dye using ZnO-CdS core-shell nano-structure coated on glass by Doctor Blade method. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Feb 25;137:160-4. doi: 10.1016/j.saa.2014.08.110. Epub 2014 Sep 6. PubMed PMID: 25218225. 11: Yildirim N, Gonen U. Capacity of a newly isolated fungus Pleurotus eryngii from Tunceli, Ovacik for chemical oxygen demand reduction and biodecolorization of Azo-Dye Congo Red. Cell Mol Biol (Noisy-le-grand). 2015 Jun 7;61(3):8-11. PubMed PMID: 26068912. 12: Reichhardt C, McCrate OA, Zhou X, Lee J, Thongsomboon W, Cegelski L. Influence of the amyloid dye Congo red on curli, cellulose, and the extracellular matrix in E. coli during growth and matrix purification. Anal Bioanal Chem. 2016 Nov;408(27):7709-7717. Epub 2016 Aug 31. PubMed PMID: 27580606. 13: Zhang LL, Liao YW, Gao HJ, Wang ZZ, Shuai C. [Removal Congo Red from Aqueous Solution Using Poly (AM-co-DVB)]. Huan Jing Ke Xue. 2015 Jun;36(6):2195-202. Chinese. PubMed PMID: 26387325. 14: Khanjani S, Morsali A. Ultrasound-promoted coating of MOF-5 on silk fiber and study of adsorptive removal and recovery of hazardous anionic dye "congo red". Ultrason Sonochem. 2014 Jul;21(4):1424-9. doi: 10.1016/j.ultsonch.2013.12.012. Epub 2013 Dec 21. PubMed PMID: 24412182. 15: Yin B, Zhang S, Jiao Y, Liu Y, Qu F, Ma Y, Wu X. Removal of Congo red dye molecules by MnO2 nanorods. J Nanosci Nanotechnol. 2014 Sep;14(9):7157-60. PubMed PMID: 25924384. 16: Hernández-Zamora M, Cristiani-Urbina E, Martínez-Jerónimo F, Perales-Vela HV, Ponce-Noyola T, Montes-Horcasitas Mdel C, Cañizares-Villanueva RO. Bioremoval of the azo dye Congo Red by the microalga Chlorella vulgaris. Environ Sci Pollut Res Int. 2015 Jul;22(14):10811-23. doi: 10.1007/s11356-015-4277-1. Epub 2015 Mar 14. PubMed PMID: 25772869. 17: Kong F, Wang A, Cheng H, Liang B. Accelerated decolorization of azo dye Congo red in a combined bioanode-biocathode bioelectrochemical system with modified electrodes deployment. Bioresour Technol. 2014 Jan;151:332-9. doi: 10.1016/j.biortech.2013.10.027. Epub 2013 Oct 21. PubMed PMID: 24262842. 18: Satheesh Babu S, Mohandass C, Vijayaraj AS, Dhale MA. Detoxification and color removal of Congo red by a novel Dietzia sp. (DTS26) - a microcosm approach. Ecotoxicol Environ Saf. 2015 Apr;114:52-60. doi: 10.1016/j.ecoenv.2015.01.002. Epub 2015 Jan 16. PubMed PMID: 25600715. 19: Ljubas D, Smoljanić G, Juretić H. Degradation of Methyl Orange and Congo Red dyes by using TiO2 nanoparticles activated by the solar and the solar-like radiation. J Environ Manage. 2015 Sep 15;161:83-91. doi: 10.1016/j.jenvman.2015.06.042. Epub 2015 Jul 6. PubMed PMID: 26160663. 20: Frid P, Anisimov SV, Popovic N. Congo red and protein aggregation in neurodegenerative diseases. Brain Res Rev. 2007 Jan;53(1):135-60. Epub 2006 Sep 7. Review. PubMed PMID: 16959325.