Azt-pmap | CAS#142629-81-0 | anti-HIV nucleoside analogue

MedKoo Cat#: 596800 | Name: Azt-pmap

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Azt-pmap is a novel aryl phosphate derivative of the anti-HIV nucleoside analogue.

Chemical Structure

Azt-pmap

CAS#142629-81-0

Theoretical Analysis

MedKoo Cat#: 596800

Name: Azt-pmap

CAS#: 142629-81-0

Chemical Formula: C20H26N6O8P

Exact Mass: 509.1550

Molecular Weight: 509.43

Elemental Analysis: C, 47.15; H, 5.14; N, 16.50; O, 25.12; P, 6.08

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Azt-pmap; Azt pmap; Aztpmap; AZT;

IUPAC/Chemical Name

L-Alanine, N-(3'-azido-3'-deoxy-P-phenyl-5'-thymidylyl)-, methyl ester

InChi Key

QQRZTJDLOOUPRA-QMCVQRASSA-N

InChi Code

InChI=1S/C20H26N6O8P/c1-12-10-26(20(29)22-18(12)27)17-9-15(23-25-21)16(34-17)11-33-35(30,31,14-7-5-4-6-8-14)24-13(2)19(28)32-3/h4-8,10,13,15-17H,9,11H2,1-3H3,(H,22,27,29)(H2,24,30,31)/t13-,15-,16+,17+/m0/s1

SMILES Code

C[C@@H](C(OC)=O)NP(OC[C@@H]1[C@@H](N=[N+]=[N-])C[C@H](N2C(NC(C(C)=C2)=O)=O)O1)(O)(C3=CC=CC=C3)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 509.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: McGuigan C, Pathirana RN, Mahmood N, Devine KG, Hay AJ. Aryl phosphate derivatives of AZT retain activity against HIV1 in cell lines which are resistant to the action of AZT. Antiviral Res. 1992 Apr;17(4):311-21. PubMed PMID: 1642482.