MedKoo Cat#: 596727 | Name: Epinephrine HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Epinephrine HCl is a hormone, neurotransmitter, and medication. Epinephrine is normally produced by both the adrenal glands and certain neurons. It plays an important role in the fight-or-flight response by increasing blood flow to muscles, output of the heart, pupil dilation, and blood sugar. It does this by binding to alpha and beta receptors. It is found in many animals and some single cell organisms.

Chemical Structure

Epinephrine HCl
Epinephrine HCl
CAS#55-31-2 (HCl)

Theoretical Analysis

MedKoo Cat#: 596727

Name: Epinephrine HCl

CAS#: 55-31-2 (HCl)

Chemical Formula: C9H14ClNO3

Exact Mass: 0.0000

Molecular Weight: 219.66

Elemental Analysis: C, 49.21; H, 6.42; Cl, 16.14; N, 6.38; O, 21.85

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Epinephrine hydrochloride; Epinephrine HCl; Adrenaline hydrochloride; Adrenaline HCl; l-Adrenaline chloride; (-)-Epinephrine hydrochloride
IUPAC/Chemical Name
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol;hydrochloride
InChi Key
ATADHKWKHYVBTJ-FVGYRXGTSA-N
InChi Code
InChI=1S/C9H13NO3.ClH/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;/h2-4,9-13H,5H2,1H3;1H/t9-;/m0./s1
SMILES Code
OC1=CC=C([C@@H](O)CNC)C=C1O.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 219.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Lam-Ubol A, Kitrueangphatchara K, Putthanuparp T, Arayakhun R, Kwanthong R, Choonhawarakorn K. Nonformalin Fixative Agents: A Comparative Study of Fixative Efficacy and Histomorphology. Int J Surg Pathol. 2018 Jun 1:1066896918779450. doi: 10.1177/1066896918779450. [Epub ahead of print] PubMed PMID: 29873279. 2: Xing SG, Mao T. The use of local anaesthesia with epinephrine in the harvest and transfer of an extended Segmuller flap in the fingers. J Hand Surg Eur Vol. 2018 Jan 1:1753193418780560. doi: 10.1177/1753193418780560. [Epub ahead of print] PubMed PMID: 29871569. 3: Moritz S, Schoessler S. Steps to Stock: Keeping Students Safe With Fully Implemented Stock Epinephrine. NASN Sch Nurse. 2018 Jun 1:1942602X18774780. doi: 10.1177/1942602X18774780. [Epub ahead of print] PubMed PMID: 29870290. 4: Shaikh N, Dy P, Basnet A, Shah S. Uncommon presentation of a common disease: influenza A presenting as adult croup . BMJ Case Rep. 2018 Jun 4;2018. pii: bcr-2017-223974. doi: 10.1136/bcr-2017-223974. PubMed PMID: 29866674. 5: Ahmad AA, Yi LM, Ahmad AR. Plating of Distal Radius Fracture Using the Wide-Awake Anesthesia Technique. J Hand Surg Am. 2018 Jun 1. pii: S0363-5023(17)32074-9. doi: 10.1016/j.jhsa.2018.03.033. [Epub ahead of print] Review. PubMed PMID: 29866390. 6: Qian XK, Xia YL, Dou TY, Hou J, Ma H, Ge GB, Yang L, Bi XL. [The relationship between catechol O-methyltransferase and diseases]. Yao Xue Xue Bao. 2016 Apr;51(4):543-51. Chinese. PubMed PMID: 29859522. 7: Wasserman RL, Hague AR, Pence DM, Sugerman RW, Silvers SK, Rolen JG, Herbert M. Real World Experience With Peanut Oral Immunotherapy: Lessons Learned From 270 Patients. J Allergy Clin Immunol Pract. 2018 May 30. pii: S2213-2198(18)30345-3. doi: 10.1016/j.jaip.2018.05.023. [Epub ahead of print] PubMed PMID: 29859333. 8: Léopold V, Gayat E, Pirracchio R, Spinar J, Parenica J, Tarvasmäki T, Lassus J, Harjola VP, Champion S, Zannad F, Valente S, Urban P, Chua HR, Bellomo R, Popovic B, Ouweneel DM, Henriques JPS, Simonis G, Lévy B, Kimmoun A, Gaudard P, Basir MB, Markota A, Adler C, Reuter H, Mebazaa A, Chouihed T. Epinephrine and short-term survival in cardiogenic shock: an individual data meta-analysis of 2583 patients. Intensive Care Med. 2018 Jun 1. doi: 10.1007/s00134-018-5222-9. [Epub ahead of print] Review. PubMed PMID: 29858926. 9: Jouffroy R, Saade A, Alexandre P, Philippe P, Carli P, Vivien B. Epinephrine administration in non-shockable out-of-hospital cardiac arrest. Am J Emerg Med. 2018 May 25. pii: S0735-6757(18)30435-2. doi: 10.1016/j.ajem.2018.05.055. [Epub ahead of print] PubMed PMID: 29857945. 10: Chen L, Tsui MMP, Shi Q, Hu C, Wang Q, Zhou B, Lam PKS, Lam JCW. Accumulation of perfluorobutane sulfonate (PFBS) and impairment of visual function in the eyes of marine medaka after a life-cycle exposure. Aquat Toxicol. 2018 May 25;201:1-10. doi: 10.1016/j.aquatox.2018.05.018. [Epub ahead of print] PubMed PMID: 29857243. 11: Diebel ME, Martin JV, Diebel LN, Liberati DM. Acute hyperglycemia exacerbates trauma induced endothelial and glycocalyx injury: An in vitro model. J Trauma Acute Care Surg. 2018 May 30. doi: 10.1097/TA.0000000000001993. [Epub ahead of print] PubMed PMID: 29851906. 12: Portaro S, Gugliandolo A, Scionti D, Cammaroto S, Morabito R, Leonardi S, Fraggetta F, Bramanti P, Mazzon E. When dysphoria is not a primary mental state: A case report of the role of the aromatic L-aminoacid decarboxylase. Medicine (Baltimore). 2018 Jun;97(22):e10953. doi: 10.1097/MD.0000000000010953. PubMed PMID: 29851841. 13: Bylund W, Delahanty L, Cooper M. The Case of Ketamine Allergy. Clin Pract Cases Emerg Med. 2017 Oct 3;1(4):323-325. doi: 10.5811/cpcem.2017.7.34405. eCollection 2017 Nov. PubMed PMID: 29849335; PubMed Central PMCID: PMC5965205. 14: Bostick DS, McCurdy MT. Catecholamine-induced Ischemic Necrosis of the Hand. Clin Pract Cases Emerg Med. 2017 Jul 14;1(3):270-271. doi: 10.5811/cpcem.2017.4.33513. eCollection 2017 Aug. PubMed PMID: 29849314; PubMed Central PMCID: PMC5965190. 15: Chou AK, Chiu CC, Chen YW, Wang JJ, Hung CH. Phentolamine Reverses Epinephrine-Enhanced Skin Antinociception of Dibucaine in Rats. Anesth Analg. 2018 May 25. doi: 10.1213/ANE.0000000000003421. [Epub ahead of print] PubMed PMID: 29847381. 16: Wu C, Ma W, Cen Q, Cai Q, Wang J, Cao Y. A comparison of the incidence of supraventricular arrhythmias between thoracic paravertebral and intercostal nerve blocks in patients undergoing thoracoscopic surgery: A randomised trial. Eur J Anaesthesiol. 2018 May 29. doi: 10.1097/EJA.0000000000000837. [Epub ahead of print] PubMed PMID: 29847363. 17: Malisch JL, Bennett DJ, Davidson BA, Wenker EE, Suzich RN, Johnson EE. Stress-Induced Hyperglycemia in White-Throated and White-Crowned Sparrows: A New Technique for Rapid Glucose Measurement in the Field. Physiol Biochem Zool. 2018 Jul/Aug;91(4):943-949. doi: 10.1086/698536. PubMed PMID: 29847208. 18: Snow SJ, Henriquez AR, Costa DL, Kodavanti UP. Neuroendocrine regulation of air pollution health effects: Emerging insights. Toxicol Sci. 2018 May 28. doi: 10.1093/toxsci/kfy129. [Epub ahead of print] PubMed PMID: 29846720. 19: Wu Y, Zeng Y, Bao X, Xiong H, Fan X, Shen B. Application of tranexamic acid and diluted epinephrine in primary total hip arthroplasty. Blood Coagul Fibrinolysis. 2018 May 24. doi: 10.1097/MBC.0000000000000743. [Epub ahead of print] PubMed PMID: 29846276. 20: Gough CJR, Nolan JP. The role of adrenaline in cardiopulmonary resuscitation. Crit Care. 2018 May 29;22(1):139. doi: 10.1186/s13054-018-2058-1. Review. PubMed PMID: 29843791; PubMed Central PMCID: PMC5975505.