L 687384 | CAS#95417-67-7 | high-affinity sigma receptor ligand

MedKoo Cat#: 596631 | Name: L 687384

Description:

WARNING: This product is for research use only, not for human or veterinary use.

L 687384 is a high-affinity sigma receptor ligand.

Chemical Structure

L 687384

CAS#95417-67-7

Theoretical Analysis

MedKoo Cat#: 596631

Name: L 687384

CAS#: 95417-67-7

Chemical Formula: C21H25N

Exact Mass: 291.1987

Molecular Weight: 291.43

Elemental Analysis: C, 86.55; H, 8.65; N, 4.81

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

L 687384; L-687384; L687384; L-687,384; L 687,384; L687,384;

IUPAC/Chemical Name

1'-benzyl-3,4-dihydro-2H-spiro[naphthalene-1,4'-piperidine]

InChi Key

MLDCBJPLHBPJET-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H25N/c1-2-7-18(8-3-1)17-22-15-13-21(14-16-22)12-6-10-19-9-4-5-11-20(19)21/h1-5,7-9,11H,6,10,12-17H2

SMILES Code

C12=C(C3(CCN(CC4=CC=CC=C4)CC3)CCC2)C=CC=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 291.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Couture S, Debonnel G. Some of the effects of the selective sigma ligand (+)pentazocine are mediated via a naloxone-sensitive receptor. Synapse. 2001 Mar 15;39(4):323-31. PubMed PMID: 11169783. 2: Bergeron R, Debonnel G. Effects of low and high doses of selective sigma ligands: further evidence suggesting the existence of different subtypes of sigma receptors. Psychopharmacology (Berl). 1997 Feb;129(3):215-24. PubMed PMID: 9084059. 3: McLarnon J, Sawyer D, Church J. The actions of L-687,384, a sigma receptor ligand, on NMDA-induced currents in cultured rat hippocampal pyramidal neurons. Neurosci Lett. 1994 Jun 20;174(2):181-4. PubMed PMID: 7526288.