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MedKoo Cat#: 596603 | Name: L 653328

Description:

WARNING: This product is for research use only, not for human or veterinary use.

L 653328 is an ocular hypotensive agent with modest beta receptor blocking activity.

Chemical Structure

L 653328
L 653328
CAS#115609-61-5

Theoretical Analysis

MedKoo Cat#: 596603

Name: L 653328

CAS#: 115609-61-5

Chemical Formula: C17H27NO4

Exact Mass: 309.1940

Molecular Weight: 309.40

Elemental Analysis: C, 65.99; H, 8.80; N, 4.53; O, 20.68

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
L 653328; L-653328; L653328; L-653,328; L653,328; L 653,328;
IUPAC/Chemical Name
(S)-4-(3-(tert-butylamino)-2-hydroxypropoxy)phenethyl acetate
InChi Key
YSAYHFMJDLPBGB-HNNXBMFYSA-N
InChi Code
InChI=1S/C17H27NO4/c1-13(19)21-10-9-14-5-7-16(8-6-14)22-12-15(20)11-18-17(2,3)4/h5-8,15,18,20H,9-12H2,1-4H3/t15-/m0/s1
SMILES Code
O[C@@H](CNC(C)(C)C)COC1=CC=C(CCOC(C)=O)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 309.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Bauer KG, Brunner-Ferber F, Distlerath LM, Lippa EA, Binkowitz B, Till P, Kaik GA. Assessment of bronchial effects following topical administration of butylamino-phenoxy-propanol-acetate, an oculoselective beta-adrenoceptor blocker in asthmatic subjects. Br J Clin Pharmacol. 1992 Aug;34(2):122-9. PubMed PMID: 1358158; PubMed Central PMCID: PMC1381528. 2: Gerin G, Durand-Cavagna G, Gordon LR, Duprat P, Hollander CF. Drug-induced changes in dogs after long term application of a beta-blocker. Lens Eye Toxic Res. 1989;6(1-2):319-29. PubMed PMID: 2577307. 3: Sugrue MF, Gautheron P, Grove J, Mallorga P, Viader MP, Baldwin JJ, Ponticello GS, Varga SL. L-653,328: an ocular hypotensive agent with modest beta receptor blocking activity. Invest Ophthalmol Vis Sci. 1988 May;29(5):776-84. PubMed PMID: 2896641.