A-446 is a novel potent and selective inhibitor of GLS (IC50 = 31 nM), targeting the allosteric site at the dimer‐dimer interface.
MedKoo Cat#: 465913
Name: A-446
CAS#: unknown
Chemical Formula: C19H19N7OS
Exact Mass: 393.1372
Molecular Weight: 393.47
Elemental Analysis: C, 58.00; H, 4.87; N, 24.92; O, 4.07; S, 8.15
The following data is based on the product molecular weight 393.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
