MedKoo Cat#: 145745 | Name: Pyrocoll

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pyrocoll is a type of compound formed from the breakdown of collagen, particularly during its degradation process. It is a biomarker that is often used in research to monitor the turnover and breakdown of collagen in the body. Pyrocoll is typically associated with the degradation of type I and type III collagen fibers, and its presence is often measured in studies related to diseases or conditions involving connective tissue, such as osteoarthritis, aging, or certain skin conditions. It’s considered a useful marker for assessing the rate of collagen degradation in various biological processes.

Chemical Structure

Pyrocoll
Pyrocoll
CAS#484-73-1

Theoretical Analysis

MedKoo Cat#: 145745

Name: Pyrocoll

CAS#: 484-73-1

Chemical Formula: C10H6N2O2

Exact Mass: 186.0400

Molecular Weight: 186.17

Elemental Analysis: C, 64.52; H, 3.25; N, 15.05; O, 17.19

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Pyrocoll;
IUPAC/Chemical Name
5H,10H-dipyrrolo[1,2-a:1',2'-d]pyrazine-5,10-dione
InChi Key
USCZWOZHDDOBHQ-UHFFFAOYSA-N
InChi Code
1S/C10H6N2O2/c13-9-7-3-1-5-11(7)10(14)8-4-2-6-12(8)9/h1-6H
SMILES Code
O=C1N2C=CC=C2C(=O)N3C=CC=C13
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 186.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Dietera A, Hamm A, Fiedler HP, Goodfellow M, Müller WE, Brun R, Beil W, Bringmann G. Pyrocoll, an antibiotic, antiparasitic and antitumor compound produced by a novel alkaliphilic Streptomyces strain. J Antibiot (Tokyo). 2003 Jul;56(7):639-46. doi: 10.7164/antibiotics.56.639. PMID: 14513907. 2: Bidasee KR, Nallani K, Besch HR Jr, Dincer UD. Streptozotocin-induced diabetes increases disulfide bond formation on cardiac ryanodine receptor (RyR2). J Pharmacol Exp Ther. 2003 Jun;305(3):989-98. doi: 10.1124/jpet.102.046201. Epub 2003 Feb 20. PMID: 12606683. 3: Caspers BA, Schroeder FC, Franke S, Voigt CC. Scents of adolescence: the maturation of the olfactory phenotype in a free-ranging mammal. PLoS One. 2011;6(6):e21162. doi: 10.1371/journal.pone.0021162. Epub 2011 Jun 27. PMID: 21738615; PMCID: PMC3124483.