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MedKoo Cat#: 591317 | Name: Aflavarin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Aflavarin is a new Anti-Insectan Metabolite from the Sclerotia of Aspergillus flavus

Chemical Structure

Aflavarin
Aflavarin
CAS#144429-67-4

Theoretical Analysis

MedKoo Cat#: 591317

Name: Aflavarin

CAS#: 144429-67-4

Chemical Formula: C24H22O9

Exact Mass: 454.1264

Molecular Weight: 454.43

Elemental Analysis: C, 63.43; H, 4.88; O, 31.69

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Aflavarin;
IUPAC/Chemical Name
(3,8'-Bi-2H-1-benzopyran)-2,2'-dione, 5-(hydroxymethyl)-4,4',7,7'-tetramethoxy-5'-methyl-, (-)-
InChi Key
PQHCPIZEGQBDDY-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H22O9/c1-11-6-14(29-3)20(23-18(11)15(30-4)9-17(26)33-23)21-22(31-5)19-12(10-25)7-13(28-2)8-16(19)32-24(21)27/h6-9,25H,10H2,1-5H3
SMILES Code
O=C1C(C2=C(O3)C(C(OC)=CC3=O)=C(C)C=C2OC)=C(OC)C4=C(CO)C=C(OC)C=C4O1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 454.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Chang PK, Scharfenstein LL, Li RW, Arroyo-Manzanares N, De Saeger S, Diana Di Mavungu J. Aspergillus flavus aswA, a gene homolog of Aspergillus nidulans oefC, regulates sclerotial development and biosynthesis of sclerotium-associated secondary metabolites. Fungal Genet Biol. 2017 Jul;104:29-37. doi: 10.1016/j.fgb.2017.04.006. Epub 2017 Apr 22. PubMed PMID: 28442441. 2: Cary JW, Han Z, Yin Y, Lohmar JM, Shantappa S, Harris-Coward PY, Mack B, Ehrlich KC, Wei Q, Arroyo-Manzanares N, Uka V, Vanhaecke L, Bhatnagar D, Yu J, Nierman WC, Johns MA, Sorensen D, Shen H, De Saeger S, Diana Di Mavungu J, Calvo AM. Transcriptome Analysis of Aspergillus flavus Reveals veA-Dependent Regulation of Secondary Metabolite Gene Clusters, Including the Novel Aflavarin Cluster. Eukaryot Cell. 2015 Oct;14(10):983-97. doi: 10.1128/EC.00092-15. Epub 2015 Jul 24. PubMed PMID: 26209694; PubMed Central PMCID: PMC4588625.