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MedKoo Cat#: 562404 | Name: SCH-43478

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SCH-43478 is a non-​nucleoside antiviral agent. It has potent and selective activity against herpes simplex virus type 2 (HSV-​2).

Chemical Structure

SCH-43478
SCH-43478
CAS#112446-99-8

Theoretical Analysis

MedKoo Cat#: 562404

Name: SCH-43478

CAS#: 112446-99-8

Chemical Formula: C12H10ClN3O

Exact Mass: 247.0512

Molecular Weight: 247.68

Elemental Analysis: C, 58.19; H, 4.07; Cl, 14.31; N, 16.97; O, 6.46

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
SCH-43478; SCH 43478; SCH43478;
IUPAC/Chemical Name
4-Chloro-6-methoxy-3-methyl-1H-pyrazolo[3,4-b]quinoline
InChi Key
BQZVEXXIPVMBRN-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H10ClN3O/c1-6-10-11(13)8-5-7(17-2)3-4-9(8)14-12(10)16-15-6/h3-5H,1-2H3,(H,14,15,16)
SMILES Code
CC1=NNC2=NC3=CC=C(OC)C=C3C(Cl)=C21
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 247.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Albin R, Chase R, Risano C, Lieberman M, Ferrari E, Skelton A, Buontempo P, Cox S, DeMartino J, Wright-Minogue J, Jirau-Lucca G, Kelly J, Afonso A, Kwong AD, Rozhon EJ, O'Connell JF. SCH 43478 and analogs: in vitro activity and in vivo efficacy of novel agents for herpesvirus type 2. Antiviral Res. 1997 Aug;35(3):139-46. PubMed PMID: 9298753.