ARS-853 is a selective, covalent KRAS(G12C) inhibitor that inhibits mutant KRAS-driven signaling by binding to the GDP-bound oncoprotein and preventing activation.
MedKoo Cat#: 584444
Name: ARS-853
CAS#: 1629268-00-3
Chemical Formula: C22H29ClN4O3
Exact Mass: 432.1928
Molecular Weight: 432.95
Elemental Analysis: C, 61.03; H, 6.75; Cl, 8.19; N, 12.94; O, 11.09
The following data is based on the product molecular weight 432.95 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
