MLS000545091 | CAS#322666-76-2 | 15-LOX-2 inhibitor

MedKoo Cat#: 562821 | Name: MLS000545091

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MLS000545091 is a potent and selective mixed-type inhibitor of human epithelial 15-lipoxygenase-2 (15-LOX-2).

Chemical Structure

MLS000545091

CAS#322666-76-2

Theoretical Analysis

MedKoo Cat#: 562821

Name: MLS000545091

CAS#: 322666-76-2

Chemical Formula: C14H15ClN2O

Exact Mass: 262.0873

Molecular Weight: 262.73

Elemental Analysis: C, 64.00; H, 5.75; Cl, 13.49; N, 10.66; O, 6.09

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

MLS000545091; MLS-000545091; MLS 000545091;

IUPAC/Chemical Name

2-(4-Chlorophenyl)-5-cyclohexyl-1,3,4-oxadiazole

InChi Key

ASRSXDRAEGLYDZ-UHFFFAOYSA-N

InChi Code

InChI=1S/C14H15ClN2O/c15-12-8-6-11(7-9-12)14-17-16-13(18-14)10-4-2-1-3-5-10/h6-10H,1-5H2

SMILES Code

ClC1=CC=C(C2=NN=C(C3CCCCC3)O2)C=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 262.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Jameson JB 2nd, Kantz A, Schultz L, Kalyanaraman C, Jacobson MP, Maloney DJ, Jadhav A, Simeonov A, Holman TR. A high throughput screen identifies potent and selective inhibitors to human epithelial 15-lipoxygenase-2. PLoS One. 2014 Aug 11;9(8):e104094. doi: 10.1371/journal.pone.0104094. eCollection 2014. PubMed PMID: 25111178; PubMed Central PMCID: PMC4128814.