MedKoo Cat#: 562736 | Name: NSC10010 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NSC10010 is a potent growth inhibitor for gammaherpesvirus-associated B-lymphomas that acts through activation of both the NF-κB and c-Myc-mediated signaling pathways.

Chemical Structure

NSC10010 HCl
NSC10010 HCl
CAS#6286-09-5 (HCl)

Theoretical Analysis

MedKoo Cat#: 562736

Name: NSC10010 HCl

CAS#: 6286-09-5 (HCl)

Chemical Formula: C31H42Cl2N4O2

Exact Mass: 500.3151

Molecular Weight: 573.60

Elemental Analysis: C, 64.91; H, 7.38; Cl, 12.36; N, 9.77; O, 5.58

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
788758-30-5 (free base) 6286-09-5 (HCl)
Synonym
NSC10010; NSC-10010; NSC 10010; NSC10010 HCl; NSC10010 hydrochloride
IUPAC/Chemical Name
Quinaldine, 4,4'-(nonamethylenediimino)bis[6-methoxy-, dihydrochloride
InChi Key
PYXMJTIQBGOWBI-UHFFFAOYSA-N
InChi Code
InChI=1S/C31H40N4O2.2ClH/c1-22-18-30(26-20-24(36-3)12-14-28(26)34-22)32-16-10-8-6-5-7-9-11-17-33-31-19-23(2)35-29-15-13-25(37-4)21-27(29)31;;/h12-15,18-21H,5-11,16-17H2,1-4H3,(H,32,34)(H,33,35);2*1H
SMILES Code
CC1=NC2=CC=C(OC)C=C2C(NCCCCCCCCCNC3=CC(C)=NC4=CC=C(OC)C=C34)=C1.[H]Cl.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 573.60 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Dzeng RK, Jha HC, Lu J, Saha A, Banerjee S, Robertson ES. Small molecule growth inhibitors of human oncogenic gammaherpesvirus infected B-cells. Mol Oncol. 2015 Feb;9(2):365-76. doi: 10.1016/j.molonc.2014.09.006. Epub 2014 Sep 26. PubMed PMID: 25306391; PubMed Central PMCID: PMC4305020.