IKKß-IN-124 is an allosteric inhibitor of IκBα phosphorylation and NF-κB transcriptional activity through selective capture of the inactive conformation and hence blockade of IKKβ S177/S181 phosphorylation.
MedKoo Cat#: 564852
Name: IKKß-IN-124
CAS#: 825608-40-0
Chemical Formula: C17H26Cl2N2O3S
Exact Mass: 408.1041
Molecular Weight: 409.37
Elemental Analysis: C, 49.88; H, 6.40; Cl, 17.32; N, 6.84; O, 11.72; S, 7.83
The following data is based on the product molecular weight 409.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
