MYRA-A | CAS#3900-43-4 | apoptosis inducer

MedKoo Cat#: 562734 | Name: MYRA-A

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MYRA-A is an inducer of apoptosis in a Myc-dependent manner. It acts by inhibiting Myc-driven transformation and disrupting MYC-Max interaction.

Chemical Structure

MYRA-A

CAS#3900-43-4

Theoretical Analysis

MedKoo Cat#: 562734

Name: MYRA-A

CAS#: 3900-43-4

Chemical Formula: C19H20N2O4

Exact Mass: 340.1423

Molecular Weight: 340.37

Elemental Analysis: C, 67.05; H, 5.92; N, 8.23; O, 18.80

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

MYRA-A; MYRA A; MYRAA; NSC-339585; NSC 339585; NSC339585;

IUPAC/Chemical Name

2-[3-(Dimethylamino)propylamino]-1,4-dihydroxyanthracene-9,10-dione

InChi Key

PCIUVTQUMJMKAU-UHFFFAOYSA-N

InChi Code

InChI=1S/C19H20N2O4/c1-21(2)9-5-8-20-13-10-14(22)15-16(19(13)25)18(24)12-7-4-3-6-11(12)17(15)23/h3-4,6-7,10,20,22,25H,5,8-9H2,1-2H3

SMILES Code

O=C1C2=C(C=CC=C2)C(C3=C(O)C=C(NCCCN(C)C)C(O)=C13)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 340.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Frenzel A, Zirath H, Vita M, Albihn A, Henriksson MA. Identification of cytotoxic drugs that selectively target tumor cells with MYC overexpression. PLoS One. 2011;6(11):e27988. doi: 10.1371/journal.pone.0027988. Epub 2011 Nov 23. PubMed PMID: 22132187; PubMed Central PMCID: PMC3223192. 2: Mo H, Henriksson M. Identification of small molecules that induce apoptosis in a Myc-dependent manner and inhibit Myc-driven transformation. Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6344-9. Epub 2006 Apr 10. PubMed PMID: 16606833; PubMed Central PMCID: PMC1435363.