AD 1308 | CAS# 72320-59-3

MedKoo Cat#: 591056 | Name: AD 1308

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AD 1308 is a bioactive chemical.

Chemical Structure

AD 1308

CAS#72320-59-3

Theoretical Analysis

MedKoo Cat#: 591056

Name: AD 1308

CAS#: 72320-59-3

Chemical Formula: C21H25Cl2N3

Exact Mass: 389.1426

Molecular Weight: 390.35

Elemental Analysis: C, 64.62; H, 6.46; Cl, 18.16; N, 10.76

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

AD 1308; AD-1308; AD1308

IUPAC/Chemical Name

Quinoline, 2-(4-ethyl-1-piperazinyl)-4-phenyl-, dihydrochloride

InChi Key

YEKLOAJGHZTNED-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H23N3.2ClH/c1-2-23-12-14-24(15-13-23)21-16-19(17-8-4-3-5-9-17)18-10-6-7-11-20(18)22-21;;/h3-11,16H,2,12-15H2,1H3;2*1H

SMILES Code

CCN1CCN(C2=NC3=CC=CC=C3C(C4=CC=CC=C4)=C2)CC1.[H]Cl.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 390.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Kawashima K, Kondoh K, Ochi Y, Oka M. [Effect of AS-2646, a novel antiulcer agent on gastric mucosal defensive factors in rats]. Nihon Yakurigaku Zasshi. 1991 Aug;98(2):73-82. Japanese. PubMed PMID: 1916545. 2: Hino K, Kawashima K, Oka M, Uno H, Matsumoto J. Synthesis and antiulcer activity of the metabolites of 2-(4-ethyl-1-piperazinyl)-4-phenylquinoline dimaleate (AS-2646), a novel gastric antisecretory and antiulcer agent. Chem Pharm Bull (Tokyo). 1989 Jan;37(1):190-2. PubMed PMID: 2720848. 3: Hino K, Kawashima K, Oka M, Nagai Y, Uno H, Matsumoto J. A novel class of antiulcer agents. 4-Phenyl-2-(1-piperazinyl)quinolines. Chem Pharm Bull (Tokyo). 1989 Jan;37(1):110-5. PubMed PMID: 2720842. 4: Kimura Y, Yano S, Watanabe K. Involvement of metabolites in the inhibitory effects of 2-(4-ethyl-1-piperazinyl)-4-phenylquinoline dimaleate (AD-2646), a new quinoline derivative, on gastric acid secretion. A comparison with tricyclic antidepressants. J Pharmacobiodyn. 1989 Jan;12(1):43-9. PubMed PMID: 2542519. 5: Karasawa T, Furukawa K, Ochi Y, Ito T, Yoshida K, Shimizu M. Antidepressant properties of 2-(4-ethyl-1-piperazinyl)-4-phenylquinoline hydrochloride (AD-1308) and its mechanism of action as compared with tricyclic antidepressants. Arch Int Pharmacodyn Ther. 1980 Jun;245(2):283-302. PubMed PMID: 6773486.