Glycerin | CAS# 56-81-5| intermediate in carbohydrate and lipid metabolism

MedKoo Cat#: 581225 | Name: Glycerin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Glycerin is a trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. It is used as a solvent, emollient, pharmaceutical agent, or sweetening agent. Glycerin is also known as Glycerol. It is a colorless, odorless, viscous liquid that is sweet-tasting and non-toxic. The glycerol backbone is found in all lipids known as triglycerides. It is widely used in the food industry as a sweetener and humectant and in pharmaceutical formulations. Glycerol has three hydroxyl groups that are responsible for its solubility in water and its hygroscopic nature.

Chemical Structure

Glycerin

CAS#56-81-5

Theoretical Analysis

MedKoo Cat#: 581225

Name: Glycerin

CAS#: 56-81-5

Chemical Formula: C3H8O3

Exact Mass: 92.0473

Molecular Weight: 92.09

Elemental Analysis: C, 39.13; H, 8.76; O, 52.12

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Glycerin; Glyceritol; Glycerolum; Osmoglyn; Optim; Propanetriol; Citifluor AF 2; Synthetic glycerine; NSC 9230; Glycerol;

IUPAC/Chemical Name

propane-1,2,3-triol

InChi Key

PEDCQBHIVMGVHV-UHFFFAOYSA-N

InChi Code

InChI=1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2

SMILES Code

C(CO)(CO)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 92.09 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Eiras CE, Marques Jde A, Prado RM, Valero MV, Bonafé EG, Zawadzki F, Perotto D, Prado IN. Glycerine levels in the diets of crossbred bulls finished in feedlot: carcass characteristics and meat quality. Meat Sci. 2014 Feb;96(2 Pt A):930-6. doi: 10.1016/j.meatsci.2013.10.002. Epub 2013 Oct 5. PubMed PMID: 24211551. 2: Shinde S, Kabra NS, Sharma SR, Avasthi BS, Ahmed J. Glycerin suppository for promoting feeding tolerance in preterm very low birthweight neonates: a randomized controlled trial. Indian Pediatr. 2014 May;51(5):367-70. PubMed PMID: 24953576. 3: Carvalho VB, Leite RF, Almeida MT, Paschoaloto JR, Carvalho EB, Lanna DP, Perez HL, Van Cleef EH, Homem Junior AC, Ezequiel JM. Carcass characteristics and meat quality of lambs fed high concentrations of crude glycerin in low-starch diets. Meat Sci. 2015 Dec;110:285-92. doi: 10.1016/j.meatsci.2015.08.001. Epub 2015 Aug 5. PubMed PMID: 26319309. 4: Bernardino VM, Rodrigues PB, de Paula Naves L, Zangeronimo MG, Alvarenga RR, Rosa PV, Santos LM, Teixeira LV. Activity of glutamate dehydrogenase and protein content in the breast of broilers fed diets containing different sources and levels of glycerine. J Anim Physiol Anim Nutr (Berl). 2014 Jun;98(3):559-68. doi: 10.1111/jpn.12113. Epub 2013 Aug 3. PubMed PMID: 23909441. 5: Fallah R, Fallahzadeh MA, Noori-Shadkam M. Evaluation of safety and efficacy of purgative manna (billinaster drop) and glycerin suppository in icterus of healthy term newborns. Curr Drug Saf. 2014 Mar;9(1):29-33. PubMed PMID: 24111649. 6: Ghaznavi AM, Nakamura M, Tepper D. An analysis of 72% chromated glycerin used for sclerotherapy: sterility, potency, and cost after extended shelf life. Dermatol Surg. 2015 Jan;41(1):121-5. doi: 10.1097/DSS.0000000000000239. PubMed PMID: 25521102. 7: Meale SJ, Chaves AV, Ding S, Bush RD, McAllister TA. Effects of crude glycerin supplementation on wool production, feeding behavior, and body condition of Merino ewes. J Anim Sci. 2013 Feb;91(2):878-85. doi: 10.2527/jas.2012-5791. Epub 2013 Jan 10. PubMed PMID: 23307856. 8: Hales KE, Bondurant RG, Luebbe MK, Cole NA, MacDonald JC. Effects of crude glycerin in steam-flaked corn-based diets fed to growing feedlot cattle. J Anim Sci. 2013 Aug;91(8):3875-80. doi: 10.2527/jas.2012-5944. Epub 2013 May 8. PubMed PMID: 23658347. 9: Hales KE, Kraich KJ, Bondurant RG, Meyer BE, Luebbe MK, Brown MS, Cole NA, MacDonald JC. Effects of glycerin on receiving performance and health status of beef steers and nutrient digestibility and rumen fermentation characteristics of growing steers. J Anim Sci. 2013 Sep;91(9):4277-89. doi: 10.2527/jas.2013-6341. Epub 2013 Jul 26. PubMed PMID: 23893984. 10: Maes L, Weemaes M, Hellinck N, De Gueldre G, Van De Steene B. Co-digestion of glycerine and sewage sludge to optimise green electricity production. Water Sci Technol. 2013;67(12):2863-7. doi: 10.2166/wst.2013.149. PubMed PMID: 23787330. 11: Mandalawi HA, Kimiaeitalab MV, Obregon V, Menoyo D, Mateos GG. Influence of source and level of glycerin in the diet on growth performance, liver characteristics, and nutrient digestibility in broilers from hatching to 21 days of age. Poult Sci. 2014 Nov;93(11):2855-63. doi: 10.3382/ps.2014-04156. Epub 2014 Sep 11. PubMed PMID: 25214552. 12: Bravo IS, Lovato G, Rodrigues JA, Ratusznei SM, Zaiat M. Biohydrogen production in an AnSBBR treating glycerin-based wastewater: effects of organic loading, influent concentration, and cycle time. Appl Biochem Biotechnol. 2015 Feb;175(4):1892-914. doi: 10.1007/s12010-014-1421-1. Epub 2014 Nov 27. PubMed PMID: 25427596. 13: Self RL. Direct analysis in real time-mass spectrometry (DART-MS) for rapid qualitative screening of toxic glycols in glycerin-containing products. J Pharm Biomed Anal. 2013 Jun;80:155-8. doi: 10.1016/j.jpba.2013.02.037. Epub 2013 Mar 26. PubMed PMID: 23584076. 14: Omazic AW, Tråvén M, Bertilsson J, Holtenius K. High- and low-purity glycerine supplementation to dairy cows in early lactation: effects on silage intake, milk production and metabolism. Animal. 2013 Sep;7(9):1479-85. doi: 10.1017/S1751731113001110. Epub 2013 Jun 26. PubMed PMID: 23800400. 15: Asakura T, Endo M, Hirayama M, Arai H, Aoki A, Tasei Y. Glycerin-Induced Conformational Changes in Bombyx mori Silk Fibroin Film Monitored by (13)C CP/MAS NMR and ¹H DQMAS NMR. Int J Mol Sci. 2016 Sep 9;17(9). pii: E1517. doi: 10.3390/ijms17091517. PubMed PMID: 27618034; PubMed Central PMCID: PMC5037794. 16: Bernardino VM, Rodrigues PB, de Paula Naves L, Rosa PV, Zangerônimo MG, Gomide EM, Saldanha MM, Alvarenga RR. Content of plasmatic glycerol and activity of hepatic glycerol kinase in broiler chickens fed diets containing different sources and concentrations of glycerine. J Anim Physiol Anim Nutr (Berl). 2014 Apr;98(2):328-37. doi: 10.1111/jpn.12083. Epub 2013 May 21. PubMed PMID: 23692650. 17: Gao HT, Xu R, Cao WX, Zhou X, Yan YH, Lu L, Xu Q, Shen Y. Food Emulsifier Glycerin Monostearate Increases Internal Exposure Levels of Six Priority Controlled Phthalate Esters and Exacerbates Their Male Reproductive Toxicities in Rats. PLoS One. 2016 Aug 30;11(8):e0161253. doi: 10.1371/journal.pone.0161253. eCollection 2016. PubMed PMID: 27575856; PubMed Central PMCID: PMC5004918. 18: Faber MO, Ferreira-Leitão VS. Optimization of biohydrogen yield produced by bacterial consortia using residual glycerin from biodiesel production. Bioresour Technol. 2016 Nov;219:365-370. doi: 10.1016/j.biortech.2016.07.141. Epub 2016 Aug 2. PubMed PMID: 27501033. 19: Levi K, Kwan A, Rhines AS, Gorcea M, Moore DJ, Dauskardt RH. Effect of glycerin on drying stresses in human stratum corneum. J Dermatol Sci. 2011 Feb;61(2):129-31. doi: 10.1016/j.jdermsci.2010.11.011. Epub 2010 Dec 4. PubMed PMID: 21177077. 20: San Vito E, Lage JF, Messana JD, Dallantonia EE, Frighetto RT, Reis RA, Neto AJ, Berchielli TT. Performance and methane emissions of grazing Nellore bulls supplemented with crude glycerin. J Anim Sci. 2016 Nov;94(11):4728-4737. doi: 10.2527/jas.2016-0530. PubMed PMID: 27898932.