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MedKoo Cat#: 571626 | Name: Sulfo-EGS Crosslinker
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sulfo-EGS Crosslinker, or Ethylene glycol bis(sulfosuccinimidylsuccinate), is a water soluble homobifunctional crosslinker. Sulfo-EGS Crosslinker can be used to label cell surface proteins as the molecule is not cell membrane permeable.

Chemical Structure

Sulfo-EGS Crosslinker
Sulfo-EGS Crosslinker
CAS#167410-92-6 (sulfo)

Theoretical Analysis

MedKoo Cat#: 571626

Name: Sulfo-EGS Crosslinker

CAS#: 167410-92-6 (sulfo)

Chemical Formula: C18H20N2O18S2

Exact Mass: 616.0153

Molecular Weight: 616.47

Elemental Analysis: C, 35.07; H, 3.27; N, 4.54; O, 46.71; S, 10.40

Price and Availability

Size Price Availability Quantity
100mg USD 550.00 2 Weeks
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Related CAS #
167410-92-6 (sulfo) 70539-42-3
Synonym
Sulfo-EGS Crosslinker
IUPAC/Chemical Name
Ethylene Glycol-Bis (Succinic Acid N-Hydroxysulfosuccinimide Ester)
InChi Key
YDFAYDGRSWSLCT-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H20N2O18S2/c21-11-7-9(39(29,30)31)17(27)19(11)37-15(25)3-1-13(23)35-5-6-36-14(24)2-4-16(26)38-20-12(22)8-10(18(20)28)40(32,33)34/h9-10H,1-8H2,(H,29,30,31)(H,32,33,34)
SMILES Code
O=C(OCCOC(CCC(ON1C(C(S(=O)(O)=O)CC1=O)=O)=O)=O)CCC(ON2C(C(S(=O)(O)=O)CC2=O)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
The 12-atom spacer arm of the Sulfo-EGS crosslinking reagent is cleavable. The Sulfo-EGS spacer arm is cleaved by hydroxylamine at pH 8.5 for 3-6 hours at 37°C. The Sulfo-EGS protein crosslinker possesses amino reactive Sulfo-NHS esters on both ends of the molecule.

Preparing Stock Solutions

The following data is based on the product molecular weight 616.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kalkhof S, Ihling C, Mechtler K, Sinz A. Chemical cross-linking and high-performance Fourier transform ion cyclotron resonance mass spectrometry for protein interaction analysis: application to a calmodulin/target peptide complex. Anal Chem. 2005 Jan 15;77(2):495-503. PubMed PMID: 15649045.