RO5508887, also known as RG-7129, is a potent BACE inhibitor with IC50 of 30 nM for BACE1, equally potent against BACE2 (IC50=40 nM).
MedKoo Cat#: 555241
Name: RO5508887 free base
CAS#: 1310347-50-2 (free base)
Chemical Formula: C18H14F3N5O2
Exact Mass: 389.1100
Molecular Weight: 389.34
Elemental Analysis: C, 55.53; H, 3.62; F, 14.64; N, 17.99; O, 8.22
The following data is based on the product molecular weight 389.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
