Mimbane hydrochloride | CAS#5560-73-6

MedKoo Cat#: 341210 | Name: Mimbane hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Mimbane hydrochloride is a biochemical.

Chemical Structure

Mimbane hydrochloride

CAS#5560-73-6

Theoretical Analysis

MedKoo Cat#: 341210

Name: Mimbane hydrochloride

CAS#: 5560-73-6

Chemical Formula: C20H27ClN2

Exact Mass: 330.1863

Molecular Weight: 330.90

Elemental Analysis: C, 72.60; H, 8.22; Cl, 10.71; N, 8.47

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Mimbane hydrochloride; W 2291A; W-2291A; W2291A.

IUPAC/Chemical Name

Yohimban, 1-methyl-, monohydrochloride

InChi Key

PGEHZROVWYXBFH-DOPHYNLBSA-N

InChi Code

InChI=1S/C20H26N2.ClH/c1-21-18-9-5-4-8-16(18)17-10-11-22-13-15-7-3-2-6-14(15)12-19(22)20(17)21;/h4-5,8-9,14-15,19H,2-3,6-7,10-13H2,1H3;1H/t14-,15-,19-;/m0./s1

SMILES Code

Cn1c2ccccc2c3c1[C@@H]4C[C@@H]5CCCC[C@H]5CN4CC3.Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 330.90 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Zhou Q, Cui L, Ren L, Wang P, Deng C, Wang Q, Fan X. Preparation of a multifunctional fibroin-based biomaterial via laccase-assisted grafting of chitooligosaccharide. Int J Biol Macromol. 2018 Mar 12;113:1062-1072. doi: 10.1016/j.ijbiomac.2018.03.042. [Epub ahead of print] PubMed PMID: 29540302. 2: Jacob JC, Sakakibara K, Mischel RA, Henderson G, Dewey WL, Akbarali HI. Ethanol Reversal of Oxycodone Tolerance in Dorsal Root Ganglia Neurons. Mol Pharmacol. 2018 May;93(5):417-426. doi: 10.1124/mol.117.110775. Epub 2018 Feb 21. PubMed PMID: 29467238. 3: Xue W, Wang P, Tu G, Yang F, Zheng G, Li X, Li X, Chen Y, Yao X, Zhu F. Computational identification of the binding mechanism of a triple reuptake inhibitor amitifadine for the treatment of major depressive disorder. Phys Chem Chem Phys. 2018 Feb 28;20(9):6606-6616. doi: 10.1039/c7cp07869b. PubMed PMID: 29451287. 4: Tian S, Li J, Tao Q, Zhao Y, Lv Z, Yang F, Duan H, Chen Y, Zhou Q, Hou D. Controlled drug delivery for glaucoma therapy using montmorillonite/Eudragit microspheres as an ion-exchange carrier. Int J Nanomedicine. 2018 Jan 12;13:415-428. doi: 10.2147/IJN.S146346. eCollection 2018. PubMed PMID: 29391798; PubMed Central PMCID: PMC5769559. 5: Mathure D, Madan JR, Gujar KN, Tupsamundre A, Ranpise HA, Dua K. Formulation and evaluation of niosomal in-situ nasal gel of Buspirone Hydrochloride for brain delivery. Pharm Nanotechnol. 2018 Jan 29. doi: 10.2174/2211738506666180130105919. [Epub ahead of print] PubMed PMID: 29380709. 6: Chang HC, Kung CC, Chang TT, Jao SC, Hsu YT, Li WS. Investigation of the proton relay system operative in human cystosolic aminopeptidase P. PLoS One. 2018 Jan 19;13(1):e0190816. doi: 10.1371/journal.pone.0190816. eCollection 2018. PubMed PMID: 29351301; PubMed Central PMCID: PMC5774706. 7: Liang L, Fu J, Qiu L. Design of pH-Sensitive Nanovesicles via Cholesterol Analogue Incorporation for Improving in Vivo Delivery of Chemotherapeutics. ACS Appl Mater Interfaces. 2018 Feb 14;10(6):5213-5226. doi: 10.1021/acsami.7b16891. Epub 2018 Jan 30. PubMed PMID: 29338184. 8: Ghaderi-Ghahfarrokhi M, Haddadi-Asl V, Zargarian SS. Fabrication and characterization of polymer-ceramic nanocomposites containing drug loaded modified halloysite nanotubes. J Biomed Mater Res A. 2018 May;106(5):1276-1287. doi: 10.1002/jbm.a.36327. Epub 2018 Jan 23. PubMed PMID: 29314595. 9: Senapati S, Shukla R, Tripathi YB, Mahanta AK, Rana D, Maiti P. Engineered Cellular Uptake and Controlled Drug Delivery Using Two Dimensional Nanoparticle and Polymer for Cancer Treatment. Mol Pharm. 2018 Feb 5;15(2):679-694. doi: 10.1021/acs.molpharmaceut.7b01119. Epub 2018 Jan 18. PubMed PMID: 29298488. 10: Tan F, Yang G, Wang Y, Chen H, Yu B, Li H, Guo J, Huang X, Deng Y, Yu P, Ding L. Icotinib inhibits EGFR signaling and alleviates psoriasis-like symptoms in animal models. Biomed Pharmacother. 2018 Feb;98:399-405. doi: 10.1016/j.biopha.2017.12.073. Epub 2017 Dec 27. PubMed PMID: 29276968. 11: Yoneda S, Yoneda N, Fukuta K, Shima T, Nakashima A, Shiozaki A, Yoshino O, Kigawa M, Yoshida T, Saito S. In which preterm labor-patients is intravenous maintenance tocolysis effective? J Obstet Gynaecol Res. 2018 Mar;44(3):397-407. doi: 10.1111/jog.13547. Epub 2017 Dec 14. PubMed PMID: 29239057. 12: Zhu Y, Wang Y, Zhou S, Jiang X, Ma X, Liu C. Robust performance of a membrane bioreactor for removing antibiotic resistance genes exposed to antibiotics: Role of membrane foulants. Water Res. 2018 Mar 1;130:139-150. doi: 10.1016/j.watres.2017.11.067. Epub 2017 Nov 30. PubMed PMID: 29216481. 13: Xu H, Medina-Sánchez M, Magdanz V, Schwarz L, Hebenstreit F, Schmidt OG. Sperm-Hybrid Micromotor for Targeted Drug Delivery. ACS Nano. 2018 Jan 23;12(1):327-337. doi: 10.1021/acsnano.7b06398. Epub 2017 Dec 13. PubMed PMID: 29202221. 14: El Sharawy AM, Shukr MH, Elshafeey AH. Formulation and optimization of duloxetine hydrochloride buccal films: in vitro and in vivo evaluation. Drug Deliv. 2017 Nov;24(1):1762-1769. doi: 10.1080/10717544.2017.1402216. PubMed PMID: 29172829. 15: Goh WJ, Zou S, Lee CK, Ou YH, Wang JW, Czarny B, Pastorin G. EXOPLEXs: Chimeric Drug Delivery Platform from the Fusion of Cell-Derived Nanovesicles and Liposomes. Biomacromolecules. 2018 Jan 8;19(1):22-30. doi: 10.1021/acs.biomac.7b01176. Epub 2017 Dec 8. PubMed PMID: 29172449. 16: Diamanti E, Gutiérrez-Pineda E, Politakos N, Andreozzi P, Rodriguez-Presa MJ, Knoll W, Azzaroni O, Gervasi CA, Moya SE. Gramicidin ion channels in a lipid bilayer supported on polyelectrolyte multilayer films: an electrochemical impedance study. Soft Matter. 2017 Dec 6;13(47):8922-8929. doi: 10.1039/c7sm01539a. PubMed PMID: 29143830. 17: Goguadze N, Zhuravliova E, Morin D, Mikeladze D, Maurice T. Sigma-1 Receptor Agonists Induce Oxidative Stress in Mitochondria and Enhance Complex I Activity in Physiological Condition but Protect Against Pathological Oxidative Stress. Neurotox Res. 2017 Nov 10. doi: 10.1007/s12640-017-9838-2. [Epub ahead of print] PubMed PMID: 29127580. 18: Wu X, Onitake H, Huang Z, Shiino T, Tahara Y, Yatabe R, Ikezaki H, Toko K. Improved Durability and Sensitivity of Bitterness-Sensing Membrane for Medicines. Sensors (Basel). 2017 Nov 4;17(11). pii: E2541. doi: 10.3390/s17112541. PubMed PMID: 29113047; PubMed Central PMCID: PMC5713652. 19: Stankowska DL, Mueller BH 2nd, Oku H, Ikeda T, Dibas A. Neuroprotective effects of inhibitors of Acid-Sensing ion channels (ASICs) in optic nerve crush model in rodents. Curr Eye Res. 2018 Jan;43(1):84-95. doi: 10.1080/02713683.2017.1383442. Epub 2017 Nov 7. PubMed PMID: 29111855. 20: Tan H, Chen L, Ma J. Penehyclidine hydrochloride post-conditioning reduces ischemia/reperfusion-induced cardiomyocyte apoptosis in rats. Exp Ther Med. 2017 Nov;14(5):4272-4278. doi: 10.3892/etm.2017.5089. Epub 2017 Sep 1. PubMed PMID: 29104640; PubMed Central PMCID: PMC5658749.