Sortin1 | CAS#503837-98-7 | sorting inhibitor

MedKoo Cat#: 562362 | Name: Sortin1

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sortin1 is a sorting inhibitor. It acts by redirecting the vacuolar destination of plant carboxypeptidase Y and other proteins in Arabidopsis suspension cells and causing these proteins to be secreted.

Chemical Structure

Sortin1

CAS#503837-98-7

Theoretical Analysis

MedKoo Cat#: 562362

Name: Sortin1

CAS#: 503837-98-7

Chemical Formula: C26H19NO6

Exact Mass: 441.1212

Molecular Weight: 441.43

Elemental Analysis: C, 70.74; H, 4.34; N, 3.17; O, 21.75

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Sortin1; Sortin-1; Sortin 1;

IUPAC/Chemical Name

4-[5-(4-Carboxy-phenyl)-furan-2-yl]-2-methyl-5-oxo-4,5-dihydro-1H-indeno[1,2-b]pyridine-3-carboxylic acid methyl ester

InChi Key

QKEXVHYWWUXESV-UHFFFAOYSA-N

InChi Code

InChI=1S/C26H19NO6/c1-13-20(26(31)32-2)21(22-23(27-13)16-5-3-4-6-17(16)24(22)28)19-12-11-18(33-19)14-7-9-15(10-8-14)25(29)30/h3-12,21,27H,1-2H3,(H,29,30)

SMILES Code

O=C(C1=C(C)NC2=C(C(C3=C2C=CC=C3)=O)C1C4=CC=C(C5=CC=C(C(O)=O)C=C5)O4)OC

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 441.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Orr DJ, Barding GA Jr, Tolley CE, Hicks GR, Raikhel NV, Larive CK. 1H NMR-based metabolomics methods for chemical genomics experiments. Methods Mol Biol. 2014;1056:225-39. doi: 10.1007/978-1-62703-592-7_21. PubMed PMID: 24306877. 2: Rosado A, Hicks GR, Norambuena L, Rogachev I, Meir S, Pourcel L, Zouhar J, Brown MQ, Boirsdore MP, Puckrin RS, Cutler SR, Rojo E, Aharoni A, Raikhel NV. Sortin1-hypersensitive mutants link vacuolar-trafficking defects and flavonoid metabolism in Arabidopsis vegetative tissues. Chem Biol. 2011 Feb 25;18(2):187-97. doi: 10.1016/j.chembiol.2010.11.015. PubMed PMID: 21338917. 3: Zouhar J, Hicks GR, Raikhel NV. Sorting inhibitors (Sortins): Chemical compounds to study vacuolar sorting in Arabidopsis. Proc Natl Acad Sci U S A. 2004 Jun 22;101(25):9497-501. Epub 2004 Jun 9. PubMed PMID: 15190181; PubMed Central PMCID: PMC439005.