MedKoo Cat#: 562348 | Name: Methylarbutin
Featured New

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Methylarbutin, also known as ß-PMP-Glc, 4-Methoxyphenyl β-D-Glucopyranoside, is an ice recrystallization inhibitor (IRI).

Chemical Structure

Methylarbutin
Methylarbutin
CAS#6032-32-2

Theoretical Analysis

MedKoo Cat#: 562348

Name: Methylarbutin

CAS#: 6032-32-2

Chemical Formula: C13H18O7

Exact Mass: 286.1053

Molecular Weight: 286.28

Elemental Analysis: C, 54.54; H, 6.34; O, 39.12

Price and Availability

Size Price Availability Quantity
100mg USD 90.00 Ready to ship
500mg USD 250.00 2 Weeks
1g USD 350.00 2 Weeks
5g USD 750.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
ß-PMP-Glc; Beta-PMP-Glc; p-Methoxyphenyl-ß-D-glucopyranoside; p-Methoxyphenyl-Beta-D-glucopyranoside;
IUPAC/Chemical Name
(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-methoxyphenoxy)tetrahydro-2H-pyran-3,4,5-triol
InChi Key
SIXFVXJMCGPTRB-UJPOAAIJSA-N
InChi Code
InChI=1S/C13H18O7/c1-18-7-2-4-8(5-3-7)19-13-12(17)11(16)10(15)9(6-14)20-13/h2-5,9-17H,6H2,1H3/t9-,10-,11+,12-,13-/m1/s1
SMILES Code
COC1=CC=C(O[C@@H]2O[C@H](CO)[C@H]([C@@H]([C@H]2O)O)O)C=C1
Appearance
Solid powder
Purity
>97% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2940.00.6000
More Info
Product Data
Certificate of Analysis
Safety Data Sheet (SDS)
Biological target:
Methylarbutin is an ice recrystallization inhibitor (IRI).
In vitro activity:
TBD
In vivo activity:
TBD
Solvent mg/mL mM comments
Solubility
Soluble in DMSO 0.0 0.00
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 286.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Flores-Bocanegra L, Pérez-Vásquez A, Torres-Piedra M, Bye R, Linares E, Mata R. α-Glucosidase Inhibitors from Vauquelinia corymbosa. Molecules. 2015 Aug 21;20(8):15330-42. doi: 10.3390/molecules200815330. PubMed PMID: 26307962; PubMed Central PMCID: PMC6332183. 2: Bousová I, Martin J, Jahodár L, Dusek J, Palicka V, Drsata J. Evaluation of in vitro effects of natural substances of plant origin using a model of protein glycoxidation. J Pharm Biomed Anal. 2005 Apr 29;37(5):957-62. PubMed PMID: 15862673. 3: Quintus J, Kovar KA, Link P, Hamacher H. Urinary excretion of arbutin metabolites after oral administration of bearberry leaf extracts. Planta Med. 2005 Feb;71(2):147-52. PubMed PMID: 15729623. 4: Dusková J, Dusek J, Jahodár L. [Bergenia crassifolia (L.) Fritsch in vitro]. Ceska Slov Farm. 2001 Mar;50(2):83-5. Czech. PubMed PMID: 11288595. 5: Lutterbach R, Stöckigt J. Dynamics of the biosynthesis of methylursubin in plant cells employing in vivo 13CNMR without labelling. Phytochemistry. 1995 Oct;40(3):801-6. PubMed PMID: 7576457. 6: Sticher O, Soldati F, Lehmann D. [High-performance liquid chromatographic separation and quantitative determination of arbutin, methylarbutin, hydroquinone and hydroquinone-monomethylether in Arctostaphylos, Bergenia, Calluna and Vaccinium species (author's transl)]. Planta Med. 1979 Mar;35(3):253-61. German. PubMed PMID: 432304. 7: CHRIST B, KUEHN G, MUELLER KH. [A photometric method for the determination of methylarbutin in bear-grape leaves (folia uvae ursi)]. Arzneimittelforschung. 1961 Feb;11:129-31. German. PubMed PMID: 13693337. 8: WAGNER G, BOHM M. [Paper chromatographic demonstration of methylarbutin by arbutin]. Pharmazie. 1957 Jun;12(6):363-6. German. PubMed PMID: 13452828.