Synonym
ß-PMP-Glc; Beta-PMP-Glc; p-Methoxyphenyl-ß-D-glucopyranoside; p-Methoxyphenyl-Beta-D-glucopyranoside;
IUPAC/Chemical Name
(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-methoxyphenoxy)tetrahydro-2H-pyran-3,4,5-triol
InChi Key
SIXFVXJMCGPTRB-UJPOAAIJSA-N
InChi Code
InChI=1S/C13H18O7/c1-18-7-2-4-8(5-3-7)19-13-12(17)11(16)10(15)9(6-14)20-13/h2-5,9-17H,6H2,1H3/t9-,10-,11+,12-,13-/m1/s1
SMILES Code
COC1=CC=C(O[C@@H]2O[C@H](CO)[C@H]([C@@H]([C@H]2O)O)O)C=C1
Purity
>97% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2940.00.6000
Biological target:
Methylarbutin is an ice recrystallization inhibitor (IRI).
|
Solvent |
mg/mL |
mM |
comments |
Solubility |
Soluble in DMSO |
0.0 |
0.00 |
|
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.
Preparing Stock Solutions
The following data is based on the
product
molecular weight
286.28
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Flores-Bocanegra L, Pérez-Vásquez A, Torres-Piedra M, Bye R, Linares E, Mata
R. α-Glucosidase Inhibitors from Vauquelinia corymbosa. Molecules. 2015 Aug
21;20(8):15330-42. doi: 10.3390/molecules200815330. PubMed PMID: 26307962; PubMed
Central PMCID: PMC6332183.
2: Bousová I, Martin J, Jahodár L, Dusek J, Palicka V, Drsata J. Evaluation of in
vitro effects of natural substances of plant origin using a model of protein
glycoxidation. J Pharm Biomed Anal. 2005 Apr 29;37(5):957-62. PubMed PMID:
15862673.
3: Quintus J, Kovar KA, Link P, Hamacher H. Urinary excretion of arbutin
metabolites after oral administration of bearberry leaf extracts. Planta Med.
2005 Feb;71(2):147-52. PubMed PMID: 15729623.
4: Dusková J, Dusek J, Jahodár L. [Bergenia crassifolia (L.) Fritsch in vitro].
Ceska Slov Farm. 2001 Mar;50(2):83-5. Czech. PubMed PMID: 11288595.
5: Lutterbach R, Stöckigt J. Dynamics of the biosynthesis of methylursubin in
plant cells employing in vivo 13CNMR without labelling. Phytochemistry. 1995
Oct;40(3):801-6. PubMed PMID: 7576457.
6: Sticher O, Soldati F, Lehmann D. [High-performance liquid chromatographic
separation and quantitative determination of arbutin, methylarbutin, hydroquinone
and hydroquinone-monomethylether in Arctostaphylos, Bergenia, Calluna and
Vaccinium species (author's transl)]. Planta Med. 1979 Mar;35(3):253-61. German.
PubMed PMID: 432304.
7: CHRIST B, KUEHN G, MUELLER KH. [A photometric method for the determination of
methylarbutin in bear-grape leaves (folia uvae ursi)]. Arzneimittelforschung.
1961 Feb;11:129-31. German. PubMed PMID: 13693337.
8: WAGNER G, BOHM M. [Paper chromatographic demonstration of methylarbutin by
arbutin]. Pharmazie. 1957 Jun;12(6):363-6. German. PubMed PMID: 13452828.