Synonym
Aramite; BRN 2509312; BRN-2509312; BRN2509312
IUPAC/Chemical Name
2-p-tert-Butylphenoxyisopropyl 2-chloroethyl sulfite
InChi Key
YKFRAOGHWKADFJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H23ClO4S/c1-12(20-21(17)19-10-9-16)11-18-14-7-5-13(6-8-14)15(2,3)4/h5-8,12H,9-11H2,1-4H3
SMILES Code
O=S(OC(C)COC1=CC=C(C(C)(C)C)C=C1)OCCCl
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
334.86
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Moriya F, Ishizu H, Akamatsu K. [A case of suicide suspected of poisoning from taking some agricultural chemicals]. Nihon Hoigaku Zasshi. 1991 Apr;45(2):158-65. Japanese. PubMed PMID: 1920923.
2: FLYNN RJ. Demodectic and sarcoptic mange of dogs successfully treated with aramite. J Am Vet Med Assoc. 1959 Feb 15;134(4):177-9. PubMed PMID: 13630800.
3: Carricaburu P, Lacroix R, Claude JR, Lacroix J. Electroretinographic study during acute Aramite intoxication of the white mouse. Toxicol Eur Res. 1979 Jul;2(4):195-8. PubMed PMID: 232789.
4: OSER BL, OSER M. 2-(p-tert-Butylphenoxy)isopropyl 2-chloroethyl sulfite (Aramite). II. Carcinogenicity. Toxicol Appl Pharmacol. 1962 Jan;4:70-88. PubMed PMID: 14482480.
5: FLYNN RJ. Follicular acariasis of mice caused by Psorergates simplex successfully treated with aramite. Am J Vet Res. 1959 Jan;20:198-200. PubMed PMID: 13823627.
6: POPPER H, STERNBERG SS, OSER BL, OSER M. The carcinogenic effect of aramite in rats. A study of hepatic nodules. Cancer. 1960 Sep-Oct;13:1035-46. PubMed PMID: 13737205.
7: OSER BL, OSER M. 2-(p-tert-butylphenoxy) isopropyl 2-chloroethyl sulfite (aramite). I. Acute, subacute, and chronic oral toxicity. Toxicol Appl Pharmacol. 1960 Jul;2:441-57. PubMed PMID: 14429210.
8: Blanc F, Ngoc-Huyen V, Warnet JM, Claude JR, Truhaut R. [Carcinogenic effect, on the liver, of an insecticide: aramite (author's transl)]. Toxicol Eur Res. 1978 Jan;1(1):13-21. French. PubMed PMID: 217127.
9: Claude JR, Huyen VN, Warnet JM, Blanc F. [Primary liver carcinogenesis induced by the pesticide 2-(4-tert-butylphenoxy0-1-methylethyl 2-chloroethyl sulphite (Aramite)]. C R Acad Sci Hebd Seances Acad Sci D. 1975 Sep 1;281(9):599-604. French. PubMed PMID: 174832.
10: STERNBERG SS, POPPER H, OSER BL, OSER M. Gallbladder and bile duct adenocarcinomas in dogs after long term feeding of aramite. Cancer. 1960 Jul-Aug;13:780-9. PubMed PMID: 13834488.
11: Tong SM, Feng MG. Laboratory and field evaluations of camptothecin sodium salt against phytophagous mites. Pest Manag Sci. 2016 Mar;72(3):629-36. doi: 10.1002/ps.4033. Epub 2015 May 20. PubMed PMID: 25924840.
12: Archer TE. Quantitative measurement of combinations of aramite, DDT, Toxaphene, and endrin in crop residues. Bull Environ Contam Toxicol. 1968 Mar;3(2):71-9. doi: 10.1007/BF01723729. PubMed PMID: 24190173.
