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MedKoo Cat#: 527812 | Name: HENA

Description:

WARNING: This product is for research use only, not for human or veterinary use.

HENA is a novel activator of large conductance, voltage- and Ca2+-gated K+ (BK) channels containing KCNMB1 (ß1) subunits.

Chemical Structure

HENA
HENA
CAS#1148013-87-9

Theoretical Analysis

MedKoo Cat#: 527812

Name: HENA

CAS#: 1148013-87-9

Chemical Formula: C30H47NaO3

Exact Mass: 478.3423

Molecular Weight: 478.69

Elemental Analysis: C, 75.27; H, 9.90; Na, 4.80; O, 10.03

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
HENA
IUPAC/Chemical Name
(3b,20b)-3-Hydroxy-olean-12-en-29-oic acid sodium salt
InChi Key
UDJPLVCFJFTZAA-DAXBFPKBSA-M
InChi Code
InChI=1S/C30H48O3.Na/c1-25(2)21-10-13-30(7)22(28(21,5)12-11-23(25)31)9-8-19-20-18-27(4,24(32)33)15-14-26(20,3)16-17-29(19,30)6;/h8,20-23,31H,9-18H2,1-7H3,(H,32,33);/q;+1/p-1/t20-,21-,22+,23-,26+,27+,28-,29+,30+;/m0./s1
SMILES Code
CC1(C)[C@@H](O)CC[C@]2(C)[C@@]3([H])CC=C4[C@]5([H])C[C@](C)(C([O-])=O)CC[C@@](C)5CC[C@](C)4[C@@](C)3CC[C@@]12[H].[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 478.69 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wang JY, Zhou P, Wang J, Tang B, Su T, Liu XR, Li BM, Meng H, Shi YW, Yi YH, He N, Liao WP. ARHGEF9 mutations in epileptic encephalopathy/intellectual disability: toward understanding the mechanism underlying phenotypic variation. Neurogenetics. 2018 Jan;19(1):9-16. doi: 10.1007/s10048-017-0528-2. Epub 2017 Nov 13. PubMed PMID: 29130122. 2: Hena S, Znad H, Heong KT, Judd S. Dairy farm wastewater treatment and lipid accumulation by Arthrospira platensis. Water Res. 2018 Jan 1;128:267-277. doi: 10.1016/j.watres.2017.10.057. Epub 2017 Oct 28. PubMed PMID: 29107911. 3: Hena KM, Yip J, Jaber N, Goldfarb D, Fullam K, Cleven K, Moir W, Zeig-Owens R, Webber MP, Spevack DM, Judson MA, Maier L, Krumerman A, Aizer A, Spivack SD, Berman J, Aldrich TK, Prezant DJ; FDNY Sarcoidosis Clinical Research Group*. Clinical Course of Sarcoidosis in World Trade Center-Exposed Firefighters. Chest. 2018 Jan;153(1):114-123. doi: 10.1016/j.chest.2017.10.014. Epub 2017 Oct 21. PubMed PMID: 29066387. 4: Patel H, Williams KA Sr, Marinescu K. What is this image? 2017: image 3 result : Incidental findings during myocardial perfusion imaging. J Nucl Cardiol. 2017 Dec;24(6):1846-1847. doi: 10.1007/s12350-017-1084-8. PubMed PMID: 29043553. 5: Muneeb A, Jawaid H, Khalid N, Mian A. The Art of Healing through Narrative Medicine in Clinical Practice: A Reflection. Perm J. 2017;21. doi: 10.7812/TPP/17-013. PubMed PMID: 29035184; PubMed Central PMCID: PMC5638639. 6: Hena Z, Sutton NJ, Gates GJ, Taragin BH, Pass RH. Initial experience with the 3.3 Fr Mongoose(®) pigtail catheter for aortic angiography during patent ductus arteriosus closure in small patients. Ann Pediatr Cardiol. 2017 Sep-Dec;10(3):240-244. doi: 10.4103/apc.APC_9_17. PubMed PMID: 28928609; PubMed Central PMCID: PMC5594934. 7: Nettely T, Rajaee AH, Denil NA, Idris MH, Nesarul MH, Amin SMN, Hena MKA. Reproductive biology of Nemipterus japonicus (Bloch, 1791) from the coastal waters of Bintulu (South China Sea), Sarawak, Malaysia. J Environ Biol. 2016 Jul;37(4 Spec No):715-24. PubMed PMID: 28779731. 8: Hamli H, Idris MH, Abu Hena MK, Rajaee AH, Arshad A. Inner shell as variation key of local hard clam Meretrix spp. J Environ Biol. 2016 Jul;37(4 Spec No):641-6. PubMed PMID: 28779722. 9: Cleven KL, Webber MP, Zeig-Owens R, Hena KM, Prezant DJ. Airway Disease in Rescue/Recovery Workers: Recent Findings from the World Trade Center Collapse. Curr Allergy Asthma Rep. 2017 Jan;17(1):5. doi: 10.1007/s11882-017-0670-9. Review. PubMed PMID: 28181152. 10: Waseem H, Vivas AC, Vale FL. MRI-guided laser interstitial thermal therapy for treatment of medically refractory non-lesional mesial temporal lobe epilepsy: Outcomes, complications, and current limitations: A review. J Clin Neurosci. 2017 Apr;38:1-7. doi: 10.1016/j.jocn.2016.12.002. Epub 2016 Dec 23. Review. PubMed PMID: 28024732. 11: Toscani A, Jantan KA, Hena JB, Robson JA, Parmenter EJ, Fiorini V, White AJP, Stagni S, Wilton-Ely JDET. The stepwise generation of multimetallic complexes based on a vinylbipyridine linkage and their photophysical properties. Dalton Trans. 2017 May 2;46(17):5558-5570. doi: 10.1039/c6dt03810g. PubMed PMID: 27872923. 12: Hotz A, Hena Z, Gross E. A Case of Back Pain That Wakes a Child From Sleep. JAMA Pediatr. 2016 Nov 1;170(11):1101-1102. doi: 10.1001/jamapediatrics.2016.0454. PubMed PMID: 27820627. 13: Fan LL, Xue XZ, Jiao N. In vitro effect of IL-17D on human ovarian carcinoma cells and inherent immunity. J Biol Regul Homeost Agents. 2016 Jul-Sep;30(3):815-820. PubMed PMID: 27655504. 14: Lavania M, Hena A, Reja H, Nigam A, Biswas NK, Singh I, Turankar RP, Gupta U, Kumar S, Rewaria L, Patra PK, Sengupta U, Bhattacharya B. Mutation at codon 442 in the rpoB gene of Mycobacterium leprae does not confer resistance to rifampicin. Lepr Rev. 2016 Mar;87(1):93-100. PubMed PMID: 27255062. 15: Hena S, Rozi R, Tabassum S, Huda A. Simultaneous removal of potent cyanotoxins from water using magnetophoretic nanoparticle of polypyrrole: adsorption kinetic and isotherm study. Environ Sci Pollut Res Int. 2016 Aug;23(15):14868-80. doi: 10.1007/s11356-016-6540-5. Epub 2016 Apr 12. PubMed PMID: 27072032. 16: Alam DS, Talukder SH, Chowdhury MA, Siddiquee AT, Ahmed S, Pervin S, Khan S, Hasan K, Koehlmoos TL, Niessen LW. Overweight and abdominal obesity as determinants of undiagnosed diabetes and pre-diabetes in Bangladesh. BMC Obes. 2016 Mar 18;3:19. doi: 10.1186/s40608-016-0099-z. eCollection 2016. PubMed PMID: 27004127; PubMed Central PMCID: PMC4797177. 17: Gao AS, Du H, Gao Q, Wang YJ, Wang XY, Liu JW, Lu B. Tong Luo Jiu Nao, a Chinese Medicine Formula, Reduces Inflammatory Stress in a Mouse Model of Alzheimer's Disease. Am J Alzheimers Dis Other Demen. 2016 Aug;31(5):413-21. doi: 10.1177/1533317515628051. Epub 2016 Mar 17. PubMed PMID: 26993489. 18: Hena KM, Eisen LA, Shiloh AL. A Man in His 60s With Renal Failure and Shock Refractory to Vasopressors. Chest. 2015 Dec;148(6):e171-e174. doi: 10.1378/chest.15-0160. PubMed PMID: 26621295. 19: Abu Hena MK, Sidik BJ, Idris MH, Nesarul MH, Aysha A, Islam MS, Nazmul H. Forest structure and litter production of naturally re-generated white mangrove Avicennia marina in sub-tropical estuarine coast. J Environ Biol. 2015 Sep;36(5):1199-204. PubMed PMID: 26521566. 20: Li JJ. Report: Clinical characteristics and treatment experience report of severe pulmonary infection after renal transplantation. Pak J Pharm Sci. 2015 Jul;28(4 Suppl):1559-62. PubMed PMID: 26431655.

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