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MedKoo Cat#: 562313 | Name: Clomethiazole
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Clomethiazole is a positive allosteric modulator at the barbiturate/picrotoxin site of the GABAA receptor. It acts as a sedative and hypnotic agent.

Chemical Structure

Clomethiazole
Clomethiazole
CAS#533-45-9 (free base)

Theoretical Analysis

MedKoo Cat#: 562313

Name: Clomethiazole

CAS#: 533-45-9 (free base)

Chemical Formula: C6H8ClNS

Exact Mass: 161.0066

Molecular Weight: 161.64

Elemental Analysis: C, 44.58; H, 4.99; Cl, 21.93; N, 8.67; S, 19.83

Price and Availability

Size Price Availability Quantity
50mg USD 350.00 2 Weeks
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Related CAS #
1867-58-9 (edisylate) 533-45-9 (free base) 6001-74-7 (HCl)
Synonym
Clomethiazole; Chlormethiazole; Chlorethiazol; Distraneurin; Clomethiazolum; Emineurina; Somnevrin
IUPAC/Chemical Name
5-(2-Chloroethyl)-4-methyl-1,3-thiazole
InChi Key
PCLITLDOTJTVDJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C6H8ClNS/c1-5-6(2-3-7)9-4-8-5/h4H,2-3H2,1H3
SMILES Code
CC1=C(CCCl)SC=N1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 161.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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