Synonym
DA 1686; BRN 1029299; DA-1686; DA1686;
IUPAC/Chemical Name
1,5-Dimorpholino-3-(1-naphthyl)-pentane
InChi Key
AVBHUVFGLRWOSS-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H32N2O2/c1-2-6-22-20(4-1)5-3-7-23(22)21(8-10-24-12-16-26-17-13-24)9-11-25-14-18-27-19-15-25/h1-7,21H,8-19H2
SMILES Code
C(CCN1CCOCC1)(C2=C3C=CC=CC3=CC=C2)CCN4CCOCC4
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
368.52
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Bianchi C, Bruzzese T, Casadio S, Coppi G, Pala G, Sanna GP, Turba C. Anti-arrhythmic properties of 1,5-dimorpholino-3-(1-naphthyl)-pentane: DA 1686. Experientia. 1967 Apr 15;23(4):243-4. PubMed PMID: 6055916.
2: Bianchi C, Sanna GP, Turba C. Anti-arrhythmic properties of 1,5-dimorpholino-3-(1-naphthyl)-pentane (DA 1686). Arzneimittelforschung. 1968 Jul;18(7):845-50. PubMed PMID: 5755831.
3: Coppi G, Bonardi G, Perego R. Absorption, excretion and metabolism of 1,5-dimorpholino-3-(1-naphthyl)-pentane (DA 1686) in rats and rabbits. Arzneimittelforschung. 1968 Oct;18(10):1343-5. PubMed PMID: 5755717.
4: Turba C, Sanna GP, Bianchi C. Acute toxicity and general pharmacologic properties of 1,5-dimorpholino-3-(1-naphthyl)-pentane: DA 1686. Arzneimittelforschung. 1968 Sep;18(9):1127-32. PubMed PMID: 4387882.
5: Coppi G, Bonardi G, Marazzi-Uberti E, Bianchi C. Toxicologic investigations on a new anti-arrhythmic compound: 1,5-dimorpholino-3-(l-naphthyl)-pentane (DA 1686). Arzneimittelforschung. 1969 Feb;19(2):156-61. PubMed PMID: 4305820.
