MedKoo Cat#: 563852 | Name: P516-0475

Description:

WARNING: This product is for research use only, not for human or veterinary use.

P516-0475 is a novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO. This compound induces quorum sensing by stabilizing SHP pheromones in culture.

Chemical Structure

P516-0475
P516-0475
CAS#1359627-33-0

Theoretical Analysis

MedKoo Cat#: 563852

Name: P516-0475

CAS#: 1359627-33-0

Chemical Formula: C15H17N5O3

Exact Mass: 315.1331

Molecular Weight: 315.33

Elemental Analysis: C, 57.13; H, 5.43; N, 22.21; O, 15.22

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
P516-0475; P5160475; P516 0475; P-5160475; P 5160475
IUPAC/Chemical Name
N-(3-Methoxypropyl)-7-methyl-4-oxo-4,5-dihydro-[1,2,3]triazolo[1,5-a]quinoxaline-3-carboxamide
InChi Key
IFMRJCJHUJEJJY-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H17N5O3/c1-9-4-5-11-10(8-9)17-15(22)13-12(18-19-20(11)13)14(21)16-6-3-7-23-2/h4-5,8H,3,6-7H2,1-2H3,(H,16,21)(H,17,22)
SMILES Code
O=C(C1=C2N(N=N1)C3=C(C=C(C)C=C3)NC2=O)NCCCOC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 315.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Pérez Morales TG, Ratia K, Wang DS, Gogos A, Bloem L, Driver TG, Federle MJ. A novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO. J Biol Chem. 2018 Jan 19;293(3):931-940. doi: 10.1074/jbc.M117.810994. Epub 2017 Dec 4. Erratum in: J Biol Chem. 2018 Mar 23;293(12 ):4580. Bloem, Laura [author added];. PubMed PMID: 29203527; PubMed Central PMCID: PMC5777264.