Synonym
Teflurane; Abbott 16900; Abbott-16900; Teflurano; Tefluranum; Teflurano [INN-Spanish]; Tefluranum [INN-Latin];
IUPAC/Chemical Name
2-Bromo-1,1,1,2-tetrafluoroethane
InChi Key
RZXZIZDRFQFCTA-UHFFFAOYSA-N
InChi Code
InChI=1S/C2HBrF4/c3-1(4)2(5,6)7/h1H
SMILES Code
FC(Br)C(F)(F)F
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
180.93
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Tiwari D, Goldman D, Malick WA, Madan PL. Formulation and evaluation of albuterol metered dose inhalers containing tetrafluoroethane (P134a), a non-CFC propellant. Pharm Dev Technol. 1998 May;3(2):163-74. PubMed PMID: 9653753.
2: EDELIST G, SINGER MM, EGER EI 2nd. SOLUBILITY COEFFICIENTS OF TEFLURANE IN VARIOUS BIOLOGICAL MEDIA. Anesthesiology. 1964 Mar-Apr;25:223-5. PubMed PMID: 14156555.
3: Black GW, Clarke RS, Howard PJ, McCullough H. The cardiovascular effects of teflurane in the cat. Br J Anaesth. 1969 Apr;41(4):288-96. PubMed PMID: 5780732.
4: Jones GO, Kellner GA, Wasmuth CE. Teflurane (1,1,1,2-tetra fluoro-bromethane) in clinical use. Anaesthesia. 1969 Jul;24(3):378-87. PubMed PMID: 4892959.
5: Levin K, Corssen G. Teflurane: a new halogenated gaseous anesthetic--first clinical experience. Mich Med. 1968 Apr;67(7):466-71. PubMed PMID: 4869712.
6: Artusio JF Jr, Van Poznak A, Weingram J, Sohn YJ. Teflurane, a nonexplosive gas for clinical anesthesia. Anesth Analg. 1967 Sep-Oct;46(5):657-64. PubMed PMID: 6069535.
7: Warner WA, Orth OS, Weber DL, Layton JM. Laboratory investigation of teflurane. Anesth Analg. 1967 Jan-Feb;46(1):33-8. PubMed PMID: 6066805.
