MedKoo Cat#: 562243 | Name: RS-246204

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RS-246204 is a small molecule R-spondin-1 substitute. It acts by promoting the initial formation and growth of enteroids in the medium without R-spondin-1.

Chemical Structure

RS-246204
RS-246204
CAS#878451-87-7

Theoretical Analysis

MedKoo Cat#: 562243

Name: RS-246204

CAS#: 878451-87-7

Chemical Formula: C16H13N5O2S

Exact Mass: 339.0790

Molecular Weight: 339.37

Elemental Analysis: C, 56.63; H, 3.86; N, 20.64; O, 9.43; S, 9.45

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
RS-246204; RS 246204; RS246204;
IUPAC/Chemical Name
3,7-Dimethyl-8-(quinolin-2-ylthio)-3,7-dihydro-1H-purine-2,6-dione
InChi Key
UHUHSGFUUWVRBO-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H13N5O2S/c1-20-12-13(21(2)15(23)19-14(12)22)18-16(20)24-11-8-7-9-5-3-4-6-10(9)17-11/h3-8H,1-2H3,(H,19,22,23)
SMILES Code
O=C(N1)N(C)C2=C(N(C)C(SC3=NC4=CC=CC=C4C=C3)=N2)C1=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 339.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Nam MO, Hahn S, Jee JH, Hwang TS, Yoon H, Lee DH, Kwon MS, Yoo J. Effects of a small molecule R-spondin-1 substitute RS-246204 on a mouse intestinal organoid culture. Oncotarget. 2017 Dec 26;9(5):6356-6368. doi: 10.18632/oncotarget.23721. eCollection 2018 Jan 19. PubMed PMID: 29464078; PubMed Central PMCID: PMC5814218.