IUPAC/Chemical Name
Yadanzioside B
InChi Key
ZIFQTRDEOHDYPY-CDDZGJFPSA-N
InChi Code
InChI=1S/C32H44O17/c1-10(2)6-15(34)48-22-24-31-9-45-32(24,29(43)44-5)26(41)20(39)23(31)30(4)12(7-14(31)47-27(22)42)11(3)21(19(38)25(30)40)49-28-18(37)17(36)16(35)13(8-33)46-28/h10,12-14,16-18,20,22-26,28,33,35-37,39-41H,6-9H2,1-5H3/t12-,13-,14-,16-,17+,18-,20-,22-,23-,24-,25-,26+,28+,30+,31-,32+/m1/s1
SMILES Code
C=1(C([C@H]([C@@]2([C@H]3[C@H]([C@@H]([C@@]4([C@H]5[C@@]3([C@@H](C[C@@H]2C1C)OC([C@@H]5OC(=O)CC(C)C)=O)CO4)C(=O)OC)O)O)C)O)=O)O[C@H]1[C@@H]([C@@H](O)[C@@H]([C@H](O1)CO)O)O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
700.69
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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4: Okuyama E, Gao LH, Yamazaki M. [Studies on pharmacologically active principles from Indonesian crude drugs. III. Toxic components from Brucea javanica (L.) Merr]. Yakugaku Zasshi. 1990 Nov;110(11):834-8. Japanese. PubMed PMID: 2082013.
5: Okano M, Fukamiya N, Toyota T, Tagahara K, Lee KH. Antitumor agents, 104. Isolation of yadanziosides M and P from Brucea antidysenterica and identification of bruceantinoside B as a mixture of yadanzioside P and bruceantinoside C. J Nat Prod. 1989 Mar-Apr;52(2):398-401. PubMed PMID: 2746262.
6: Sakaki T, Yoshimura S, Tsuyuki T, Takahashi T, Honda T. Yadanzioside P, a new antileukemic quassinoid glycoside from Brucea javanica (L.) Merr with the 3-O-(beta-D-glucopyranosyl)bruceantin structure. Chem Pharm Bull (Tokyo). 1986 Oct;34(10):4447-50. PubMed PMID: 3829175.
