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MedKoo Cat#: 562119 | Name: Beaucage reagent
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Beaucage reagent is a DNA cleavage reagent.

Chemical Structure

Beaucage reagent
Beaucage reagent
CAS#66304-01-6

Theoretical Analysis

MedKoo Cat#: 562119

Name: Beaucage reagent

CAS#: 66304-01-6

Chemical Formula: C7H4O3S2

Exact Mass: 199.9602

Molecular Weight: 200.22

Elemental Analysis: C, 41.99; H, 2.01; O, 23.97; S, 32.02

Price and Availability

Size Price Availability Quantity
1g USD 250.00 2 Weeks
5g USD 550.00 2 Weeks
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Related CAS #
No Data
Synonym
Beaucage reagent;
IUPAC/Chemical Name
3H-Benzo[c][1,2]dithiol-3-one 1,1-dioxide
InChi Key
JUDOLRSMWHVKGX-UHFFFAOYSA-N
InChi Code
InChI=1S/C7H4O3S2/c8-7-5-3-1-2-4-6(5)12(9,10)11-7/h1-4H
SMILES Code
O=C1C2=CC=CC=C2S(S1)(=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 200.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Manoharan M, Lu Y, Casper MD, Just G. Allyl group as a protecting group for internucleotide phosphate and thiophosphate linkages in oligonucleotide synthesis: facile oxidation and deprotection conditions. Org Lett. 2000 Feb 10;2(3):243-6. PubMed PMID: 10814292. 2: Xu Q, Musier-Forsyth K, Hammer RP, Barany G. Use of 1,2,4-dithiazolidine-3,5-dione (DtsNH) and 3-ethoxy-1,2,4-dithiazoline-5-one (EDITH) for synthesis of phosphorothioate-containing oligodeoxyribonucleotides. Nucleic Acids Res. 1996 May 1;24(9):1602-7. PubMed PMID: 8649975; PubMed Central PMCID: PMC145860. 3: Lesiak K, Khamnei S, Torrence PF. 2',5'-Oligoadenylate:antisense chimeras--synthesis and properties. Bioconjug Chem. 1993 Nov-Dec;4(6):467-72. PubMed PMID: 8305516.