eSM156 is a potent FLT3 inhibitor with single-digit nM potency and high antiproliferative activity against acute myeloid leukemia (AML) cells. eSM156 has IC50 (FLT3) = 1.4 nM; EC50 (MV4-11cells) = 150 nM; EC50 (MOLM-13 cells) = 40 nM.
MedKoo Cat#: 407883
Name: eSM156
CAS#: Unknown
Chemical Formula: C23H31N7
Exact Mass: 405.2641
Molecular Weight: 405.55
Elemental Analysis: C, 68.12; H, 7.71; N, 24.18
The following data is based on the product molecular weight 405.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |