PhiKan083, also known as PK083 is a Y220C pocket ligand which targets the p53 cancer mutant Y220C. PK083 restores p53 signaling in Y220C p53-mutated cancer cells by binding to a mutation-induced surface crevice and acting as molecular chaperones.
MedKoo Cat#: 562094
Name: PhiKan-083 HCl
CAS#: 1050480-30-2 (HCl)
Chemical Formula: C16H19ClN2
Exact Mass: 274.1237
Molecular Weight: 274.79
Elemental Analysis: C, 69.94; H, 6.97; Cl, 12.90; N, 10.19
The following data is based on the product molecular weight 274.79 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
