MedKoo Cat#: 129084 | Name: AM11638

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AM11638 is a CB1 and CB2 agonist. AM11638 Suppresses CFA-Induced Mechanical Hypersensitivity with a Longer Duration of Action Compared to Anandamide.

Chemical Structure

AM11638
AM11638
CAS#N/A

Theoretical Analysis

MedKoo Cat#: 129084

Name: AM11638

CAS#: N/A

Chemical Formula: C27H41NO2

Exact Mass: 411.3137

Molecular Weight: 411.63

Elemental Analysis: C, 78.78; H, 10.04; N, 3.40; O, 7.77

Price and Availability

Related CAS #
No Data
Synonym
AM11638; AM-11638; AM 11638
IUPAC/Chemical Name
N-((R)-1-hydroxypropan-2-yl)-4-(2-((2Z,5Z,8Z)-tetradeca-2,5,8-trien-1-yl)phenyl)butanamide
InChi Key
PHNOMOBVHWVHNY-AVEHABDLSA-N
InChi Code
InChI=1S/C27H41NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-18-25-19-15-16-20-26(25)21-17-22-27(30)28-24(2)23-29/h7-8,10-11,13-16,19-20,24,29H,3-6,9,12,17-18,21-23H2,1-2H3,(H,28,30)/b8-7-,11-10-,14-13-/t24-/m1/s1
SMILES Code
O=C(N[C@H](C)CO)CCCC1=CC=CC=C1C/C=C\C/C=C\C/C=C\CCCCC
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 411.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Georgiadis MO, Ji L, Tong F, Dang VQ, Ferreira LA, Faragher A, Tran N, Sadybekov AV, Ganapathy S, Zvonok N, Katritch V, Hohmann AG, Bohn LM, Makriyannis A, Nikas SP. Novel Tetraolefinic Chain Phenyl Substituted Endocannabinoid Probes. J Med Chem. 2025 Jun 26. doi: 10.1021/acs.jmedchem.5c00047. Epub ahead of print. PMID: 40569175.