ZM39923 HCl | CAS#58753-54-1 | JAK3 inhibitor

MedKoo Cat#: 527499 | Name: ZM39923 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ZM39923 HCl is a potent, selective inhibitor of Janus tyrosine kinase 3 (JAK3).

Chemical Structure

ZM39923 HCl

CAS#58753-54-1

Theoretical Analysis

MedKoo Cat#: 527499

Name: ZM39923 HCl

CAS#: 58753-54-1

Chemical Formula: C23H26ClNO

Exact Mass: 367.1703

Molecular Weight: 367.92

Elemental Analysis: C, 75.09; H, 7.12; Cl, 9.64; N, 3.81; O, 4.35

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

ZM 39923; ZM-39923; ZM39923 HCl

IUPAC/Chemical Name

3-[Benzyl(propan-2-yl)amino]-1-naphthalen-2-ylpropan-1-one hydrochloride

InChi Key

NJTUORMLOPXPBY-UHFFFAOYSA-N

InChi Code

InChI=1S/C23H25NO.ClH/c1-18(2)24(17-19-8-4-3-5-9-19)15-14-23(25)22-13-12-20-10-6-7-11-21(20)16-22;/h3-13,16,18H,14-15,17H2,1-2H3;1H

SMILES Code

O=C(C1=CC=C2C=CC=CC2=C1)CCN(CC3=CC=CC=C3)C(C)C.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 367.92 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Vidro-Kotchan E, Yendluri BB, Le-Thai T, Tsin A. NBHA reduces acrolein-induced changes in ARPE-19 cells: possible involvement of TGFβ. Curr Eye Res. 2011 Apr;36(4):370-8. doi: 10.3109/02713683.2010.549601. Epub 2011 Feb 10. PubMed PMID: 21309688; PubMed Central PMCID: PMC4487514.