DL-Adrenaline | CAS#329-65-7 | adrenoceptor agonist

MedKoo Cat#: 561664 | Name: DL-Adrenaline

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

DL-Adrenaline is a non-selective adrenoceptor agonist. It induces lipolysis and systemic muscle contraction, and shows systemic vasoconstrictive, bronchodilatory, positive chronotropic and gastrointestinal relaxant effects in vivo.

Chemical Structure

DL-Adrenaline

CAS#329-65-7 (free base)

Theoretical Analysis

MedKoo Cat#: 561664

Name: DL-Adrenaline

CAS#: 329-65-7 (free base)

Chemical Formula: C9H13NO3

Exact Mass: 183.0895

Molecular Weight: 183.21

Elemental Analysis: C, 59.00; H, 7.15; N, 7.65; O, 26.20

Price and Availability

Size	Price	Availability	Quantity
1g	USD 250.00	2 Weeks
5g	USD 650.00	2 weeks

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Related CAS #

329-65-7 (free base) 329-63-5 (HCl)

Synonym

DL-Adrenaline; DL Adrenaline; Racepinefrine; Racepinephrine; DL-Epinephrine; DL Epinephrine; (+/-)-Adrenaline;

IUPAC/Chemical Name

4-[1-Hydroxy-2-(methylamino)ethyl]benzene-1,2-diol

InChi Key

UCTWMZQNUQWSLP-UHFFFAOYSA-N

InChi Code

InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3

SMILES Code

OC1=CC=C(C(O)CNC)C=C1O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Product Data

Product Data

Instruction

View handling instruction

Biological target:

DL-Adrenaline is a non-selective adrenoceptor agonist.

In vitro activity:

TBD

In vivo activity:

TBD

	Solvent	mg/mL	mM
Solubility
	5% TFA	20.0	109.17

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 183.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

TBD

In vitro protocol:

TBD

In vivo protocol:

TBD

1: Graudal NA, Hubeck-Graudal T, Jurgens G. Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride. Cochrane Database Syst Rev. 2017 Apr 9;4:CD004022. doi: 10.1002/14651858.CD004022.pub4. Review. PubMed PMID: 28391629. 2: Petrocheilou A, Tanou K, Kalampouka E, Malakasioti G, Giannios C, Kaditis AG. Viral croup: diagnosis and a treatment algorithm. Pediatr Pulmonol. 2014 May;49(5):421-9. doi: 10.1002/ppul.22993. Epub 2014 Mar 5. Review. PubMed PMID: 24596395. 3: Bjornson C, Russell K, Vandermeer B, Klassen TP, Johnson DW. Nebulized epinephrine for croup in children. Cochrane Database Syst Rev. 2013 Oct 10;(10):CD006619. doi: 10.1002/14651858.CD006619.pub3. Review. PubMed PMID: 24114291. 4: Bjornson C, Russell KF, Vandermeer B, Durec T, Klassen TP, Johnson DW. Nebulized epinephrine for croup in children. Cochrane Database Syst Rev. 2011 Feb 16;(2):CD006619. doi: 10.1002/14651858.CD006619.pub2. Review. Update in: Cochrane Database Syst Rev. 2013;10:CD006619. PubMed PMID: 21328284. 5: Wiebe K, Rowe BH. Nebulized racemic epinephrine used in the treatment of severe asthmatic exacerbation: a case report and literature review. CJEM. 2007 Jul;9(4):304-8. Review. PubMed PMID: 17626698. 6: Cros AM, Hervé Y. [Acute laryngeal dyspnea]. Rev Prat. 2003 May 1;53(9):985-8. Review. French. PubMed PMID: 12816038. 7: Brown JC. The management of croup. Br Med Bull. 2002;61:189-202. Review. PubMed PMID: 11997306. 8: Davies MW, Davis PG. Nebulized racemic epinephrine for extubation of newborn infants. Cochrane Database Syst Rev. 2002;(1):CD000506. Review. PubMed PMID: 11869578. 9: Davies MW, Davis PG. Nebulized racemic epinephrine for extubation of newborn infants. Cochrane Database Syst Rev. 2001;(1):CD000506. Review. PubMed PMID: 11279697. 10: Davies MW, Davis PG. Nebulized racemic epinephrine for extubation of newborn infants. Cochrane Database Syst Rev. 2000;(2):CD000506. Review. Update in: Cochrane Database Syst Rev. 2001;(1):CD000506. Cochrane Database Syst Rev. 2002;(1):CD000506. PubMed PMID: 10796376. 11: Klassen TP. Recent advances in the treatment of bronchiolitis and laryngitis. Pediatr Clin North Am. 1997 Feb;44(1):249-61. Review. PubMed PMID: 9057793. 12: Weidmann B, Eisenbach T, Börger R, Niederle N. [Upper gastrointestinal bleeding as the first manifestation of a nonseminomatous testicular carcinoma]. Dtsch Med Wochenschr. 1996 Nov 15;121(46):1428-32. Review. German. PubMed PMID: 8974875. 13: Yang CC, Yang LY, Deng JF. Hypoglycemia following ethanol ingestion in children: report of a case. J Formos Med Assoc. 1995 May;94(5):267-70. Review. PubMed PMID: 7613261. 14: Jensen MK, Lund B, Nielsen JP. [Pseudocroup. Treatment in hospital]. Ugeskr Laeger. 1994 Nov 7;156(45):6657-60. Review. Danish. PubMed PMID: 7839475. 15: Akai H, Sanoyama K, Namai K, Miura Y, Murakami O, Hanew K, Sasaki H, Kimura N, Takahashi K, Sasano N, et al. [A case of adrenal mixed tumor of pheochromocytoma and adrenocortical adenoma presenting diabetes mellitus and hypertension]. Nihon Naibunpi Gakkai Zasshi. 1993 Aug 20;69(7):659-69. Review. Japanese. PubMed PMID: 8375553. 16: Skolnik N. Croup. J Fam Pract. 1993 Aug;37(2):165-70. Review. PubMed PMID: 8336098. 17: Dobrescu O, Geoffroy L, Rousseau E. [Acute laryngitis in children]. Pediatrie. 1992;47(3):195-200. Review. French. PubMed PMID: 1319043. 18: Skolnik NS. Treatment of croup. A critical review. Am J Dis Child. 1989 Sep;143(9):1045-9. Review. PubMed PMID: 2672782. 19: Goldhagen JL. Croup: pathogenesis and management. J Emerg Med. 1983;1(1):3-11. Review. PubMed PMID: 6386967. 20: Buchanan WT, Thayer KE. Systemic effects of epinephrine-impregnated retraction cord in fixed partial denture prosthodontics. J Am Dent Assoc. 1982 Apr;104(4):482-4. Review. PubMed PMID: 7040526.