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MedKoo Cat#: 561627 | Name: Tetramethrin
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tetramethrin is a potent insecticide that acts on an organism's nervous system.

Chemical Structure

Tetramethrin
CAS#7696-12-0

Theoretical Analysis

MedKoo Cat#: 561627

Name: Tetramethrin

CAS#: 7696-12-0

Chemical Formula: C19H25NO4

Exact Mass: 331.1784

Molecular Weight: 331.41

Elemental Analysis: C, 68.86; H, 7.60; N, 4.23; O, 19.31

Price and Availability

Size Price Availability Quantity
250mg USD 400.00 2 Weeks
1g USD 800.00 2 Weeks
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Related CAS #
No Data
Synonym
Tetramethrin; Neopinamine; Phthalthrin; Neo-pynamin; Neopinamin;
IUPAC/Chemical Name
(1,3-Dioxo-4,5,6,7-tetrahydroisoindol-2-yl)methyl 2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate
InChi Key
CXBMCYHAMVGWJQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H25NO4/c1-11(2)9-14-15(19(14,3)4)18(23)24-10-20-16(21)12-7-5-6-8-13(12)17(20)22/h9,14-15H,5-8,10H2,1-4H3
SMILES Code
O=C(C1C(C)(C)C1/C=C(C)\C)OCN(C(C2=C3CCCC2)=O)C3=O
Appearance
Solid powder
Purity
>95% (Total isomers)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 331.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zhao W, Wang W, Wu Y, Guo W, Ren W, Meng S, Yun S, Feng C. Magnetic biochar prepared from a spent mushroom substrate as an adsorbent for the analysis of pyrethroids in environmental water samples. Talanta. 2025 Mar 1;284:127195. doi: 10.1016/j.talanta.2024.127195. Epub 2024 Nov 9. PMID: 39577382. 2: Giugliano R, Armenio V, Savio V, Vaccaro E, Ciccotelli V, Vivaldi B. Monitoring of Non-Maximum-Residue-Level Pesticides in Animal Feed: A Study from 2019 to 2023. Toxics. 2024 Sep 19;12(9):680. doi: 10.3390/toxics12090680. PMID: 39330608; PMCID: PMC11435579. 3: Kang YH, Jeong HJ, Park YJ. Hydramethylnon induces mitochondria-mediated apoptosis in BEAS-2B human bronchial epithelial cells. Toxicol Appl Pharmacol. 2024 Nov;492:117102. doi: 10.1016/j.taap.2024.117102. Epub 2024 Sep 11. PMID: 39270854. 4: Kavallieratos NG, Boukouvala MC, Eleftheriadou N, Xefteri DN, Gidari DLS, Kyrpislidi VPC. The sublethal impacts of five insecticidal formulations on Oryzaephilus surinamensis behavioral traits. Pest Manag Sci. 2024 Oct;80(10):5334-5341. doi: 10.1002/ps.8262. Epub 2024 Jul 25. PMID: 39051420. 5: Feng J, Xu X, Huang W, Gong H, Sun X, Liu J, Xu C, Liu W. Enantioselective Toxicity of Tetramethrin to Different Developmental Stages of Zebrafish (Danio rerio). Toxics. 2024 Feb 13;12(2):146. doi: 10.3390/toxics12020146. PMID: 38393241; PMCID: PMC10892520. 6: Singh P, Gopi P, Rani MSS, Singh S, Pandya P. Biophysical and structural characterization of tetramethrin serum protein complex and its toxicological implications. J Mol Recognit. 2024 May;37(3):e3076. doi: 10.1002/jmr.3076. Epub 2024 Feb 17. PMID: 38366770. 7: Li Y, Li M, Duan S, Zhang S, Lu H, Guo X, Zhong K. d-Tetramethrin causes zebrafish hepatotoxicity by inducing oxidative stress and inhibiting cell proliferation. Toxicol Appl Pharmacol. 2024 Feb;483:116817. doi: 10.1016/j.taap.2024.116817. Epub 2024 Jan 11. PMID: 38215995. 8: Kavallieratos NG, Nika EP, Gounari PD. Five Surfaces Treated with d-Tetramethrin plus Acetamiprid for the Management of Tenebrio molitor and Alphitobius diaperinus: Which Is the Best? Insects. 2023 May 11;14(5):452. doi: 10.3390/insects14050452. PMID: 37233080; PMCID: PMC10231049. 9: Jurišić A, Ćupina AI, Potkonjak A, Savić S, Ivanović I, Kavran M, Žikić D, Meseldžija M, Dudić M. Bio-efficacy of permethrin/tetramethrin and lambda- cyhalothrin treatments in habitats of hard ticks (Acari, Ixodidae) populations with confirmed Borrelia spp. infection. Parasitol Res. 2023 May;122(5):1127-1138. doi: 10.1007/s00436-023-07812-8. Epub 2023 Mar 8. PMID: 36884104. 10: Arslan P. Pyrethroid-induced oxidative stress and biochemical changes in the primary mussel cell cultures. Environ Sci Pollut Res Int. 2023 Apr;30(16):48484-48490. doi: 10.1007/s11356-023-25845-5. Epub 2023 Feb 10. PMID: 36763268. 11: Ma S, Wang L, Guo G, Yu J, Di X. Systematic Stereoselectivity Evaluations of Tetramethrin Enantiomers: Stereoselective Cytotoxicity, Metabolism, and Environmental Fate in Earthworms, Soils, Vegetables, and Fruits. J Agric Food Chem. 2023 Jan 11;71(1):234-243. doi: 10.1021/acs.jafc.2c06489. Epub 2022 Dec 28. PMID: 36577083. 12: Nozawa H, Minakata K, Hasegawa K, Yamagishi I, Suzuki M, Kitamoto T, Watanabe K, Suzuki O. A fatal case involved in pyrethroid insecticide ingestion: quantification of tetramethrin and resmethrin in body fluids of a deceased by LC-MS/MS. Forensic Toxicol. 2022 Jan;40(1):189-198. doi: 10.1007/s11419-021-00594-7. Epub 2021 Sep 16. PMID: 36454491. 13: Tessier N, Boissonnot R, Desvignes V, Fröchen M, Merlo M, Blanchard O, Chevrier C, Guldner L, Mandin C, Yamada O, Volatier JL. Use and storage of pesticides at home in France (the Pesti'home survey 2014). Environ Res. 2023 Jan 1;216(Pt 2):114452. doi: 10.1016/j.envres.2022.114452. Epub 2022 Oct 17. PMID: 36257454. 14: Zhang S, Wang L, Liu H, Yang N, Yu S, Wang B. Synthesis, Crystal Structures, and Biological Activity Evaluation of Novel Xanthine Derivatives Containing a Pyrethroid Moiety. J Agric Food Chem. 2022 Oct 5;70(39):12330-12340. doi: 10.1021/acs.jafc.2c03876. Epub 2022 Sep 22. PMID: 36148494. 15: Nguyen HT, Polimati H, Annam SSP, Okello E, Thai QM, Vu TY, Tatipamula VB. Lobaric acid prevents the adverse effects of tetramethrin on the estrous cycle of female albino Wistar rats. PLoS One. 2022 Jul 1;17(7):e0269983. doi: 10.1371/journal.pone.0269983. PMID: 35776756; PMCID: PMC9249233. 16: Kavallieratos NG, Nika EP, Skourti A, Filintas CS, Goumenou TD. Short- and Long-Term Mortalities of Small and Large Larvae of Alphitobius diaperinus (Panzer) (Coleoptera: Tenebrionidae) on Concrete Surfaces Treated with Three Insecticides: Impact of Food. Insects. 2022 Apr 8;13(4):366. doi: 10.3390/insects13040366. PMID: 35447808; PMCID: PMC9027492. 17: Issa NT, Wathieu H, Glasgow E, Peran I, Parasido E, Li T, Simbulan-Rosenthal CM, Rosenthal D, Medvedev AV, Makarov SS, Albanese C, Byers SW, Dakshanamurthy S. A novel chemo-phenotypic method identifies mixtures of salpn, vitamin D3, and pesticides involved in the development of colorectal and pancreatic cancer. Ecotoxicol Environ Saf. 2022 Mar 15;233:113330. doi: 10.1016/j.ecoenv.2022.113330. Epub 2022 Feb 19. PMID: 35189517; PMCID: PMC10202418. 18: Guo Y, Huang Y, Pang S, Zhou T, Lin Z, Yu H, Zhang G, Bhatt P, Chen S. Novel Mechanism and Kinetics of Tetramethrin Degradation Using an Indigenous Gordonia cholesterolivorans A16. Int J Mol Sci. 2021 Aug 26;22(17):9242. doi: 10.3390/ijms22179242. PMID: 34502147; PMCID: PMC8431606. 19: Simaremare SRS, Hung CC, Yu TH, Hsieh CJ, Yiin LM. Association between Pesticides in House Dust and Residential Proximity to Farmland in a Rural Region of Taiwan. Toxics. 2021 Jul 30;9(8):180. doi: 10.3390/toxics9080180. PMID: 34437498; PMCID: PMC8402318. 20: Greño M, Amariei G, Boltes K, Castro-Puyana M, García MA, Marina ML. Ecotoxicity evaluation of tetramethrin and analysis in agrochemical formulations using chiral electrokinetic chromatography. Sci Total Environ. 2021 Dec 15;800:149496. doi: 10.1016/j.scitotenv.2021.149496. Epub 2021 Aug 5. PMID: 34388647.