(-)-Sparteine free base | CAS#90-39-1 | anticonvulsant

MedKoo Cat#: 561625 | Name: (-)-Sparteine free base

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

(-)-Sparteine is a quinolizidine alkaloid with antiarrhythmic (Class 1a), uterotonic, and neuromuscular effects. It blocks voltage-gated Na⁺ channels, reducing cardiac excitability, and enhances calcium mobilization to stimulate uterine contractions. Additionally, it inhibits CYP2D6, affecting drug metabolism, and acts as a nicotinic receptor antagonist. While it has some cytotoxic and antimicrobial potential, its toxicity—causing arrhythmias, hypotension, and neuromuscular blockade—has limited its clinical use.

Chemical Structure

(-)-Sparteine free base

CAS#90-39-1 (free base)

Theoretical Analysis

MedKoo Cat#: 561625

Name: (-)-Sparteine free base

CAS#: 90-39-1 (free base)

Chemical Formula: C15H26N2

Exact Mass: 234.2096

Molecular Weight: 234.38

Elemental Analysis: C, 76.87; H, 11.18; N, 11.95

Price and Availability

Size	Price	Availability	Quantity
25mg	USD 450.00	2 Weeks

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Related CAS #

90-39-1 (free base) 40411-70-9 (HCl)

Synonym

(-)-Sparteine; L-(-)-Sparteine; L-Sparteine; l-Sparteine; Lupinidin; Lupinidine; MeSH ID: D013034; Spartein;

IUPAC/Chemical Name

(7S,7aS,14S)-dodecahydro-2H,6H-7,14-methanodipyrido[1,2-a:1',2'-e][1,5]diazocine

InChi Key

SLRCCWJSBJZJBV-LOKSQKBWSA-N

InChi Code

InChI=1S/C15H26N2/c1-3-7-16-11-13-9-12(14(16)5-1)10-17-8-4-2-6-15(13)17/h12-15H,1-11H2/t12-,13-,14-,15?/m0/s1

SMILES Code

[C@@H]1(C2)C3CCCCN3C[C@H]2[C@@H]4CCCCN4C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 234.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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