A 9145C | CAS# 66753-47-7 | RNA methylase inhibitor

MedKoo Cat#: 571221 | Name: A 9145C

Description:

WARNING: This product is for research use only, not for human or veterinary use.

A 9145C is an inhibitor of RNA methylase. It also inhibits cyclopropane fatty acid synthase.

Chemical Structure

A 9145C

CAS#66753-47-7

Theoretical Analysis

MedKoo Cat#: 571221

Name: A 9145C

CAS#: 66753-47-7

Chemical Formula: C15H21N7O5

Exact Mass: 379.1604

Molecular Weight: 379.38

Elemental Analysis: C, 47.49; H, 5.58; N, 25.84; O, 21.09

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

A 9145C; A-9145C; A9145C

IUPAC/Chemical Name

(2R,5S,Z)-2,5-diamino-6-((3R,4S,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxydihydrofuran-2(3H)-ylidene)hexanoic acid

InChi Key

YNKCTZQHSHSLNN-QMTREVEQSA-N

InChi Code

InChI=1S/C15H21N7O5/c16-6(1-2-7(17)15(25)26)3-8-10(23)11(24)14(27-8)22-5-21-9-12(18)19-4-20-13(9)22/h3-7,10-11,14,23-24H,1-2,16-17H2,(H,25,26)(H2,18,19,20)/b8-3-/t6-,7+,10-,11-,14+/m0/s1

SMILES Code

O=C(O)[C@H](N)CC[C@H](N)/C=C1O[C@@H](N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]\1O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 379.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Smith DD Jr, Norton SJ. Inhibition of cyclopropane fatty acid synthase by sinefungin and A9145C. Biochem Biophys Res Commun. 1980 Jun 30;94(4):1458-62. PubMed PMID: 7396970.